A solid co-emulsifier in topical formulations to improve stability of emulsions. Can be used in rectal and vagina alternative dosage forms (cream).
Names & synonyms
|USP NF Name||
Lauroyl polyoxyl-6 glycerides
Lauroyl macrogol-6 glycerides
|UNII Code (FDA)||
|Preferred Substance Name (FDA)||
HYDROGENATED PALM/PALM KERNEL OIL PEG-6 ESTERS
|Handbook of Pharmaceutical Excipients||
Consists mainly of mono-, di- and triglycerides and PEG-6 (MW 300) mono- and diesters of lauric (C12) and stearic (C18) acids
Co-emulsifier in topical formulations often associated with Tefose® 1500. APIs solubilizer as co-surfactant.
Safety of use is inferred by substantial toxicological data and precedence of use in approved pharmaceutical products.
Main formulation technologies
Topical cream and lotion.