Get Inspired
In this section, you will find our latest blog articles and a library of webinars that you can watch on-demand without any limitation! This is also the place to read and subscribe to Addiactive, the Gattefossé magazine dedicated to personal care, as well as our most recent scientific publications.
Latest articles
Unlock the secrets of silk-inspired formulation
For centuries, silk has fascinated people with its unique combination of softness,…
- Inspiration
- Actives
The bioactive that helps skin thrive in an unpredictable world
In a world shaped by environmental volatility, a new active solution has been…
- Actives
- Exposome
- Local sourcing
- Plant sourcing
Climate-adaptive beauty
Climate change is no longer a distant concern; it is a daily reality which presents…
- Actives
- Exposome
Latest publications
Lipid mediator class-switching defects in aging skin disrupt pro-resolving pathways and compromise dermal homeostasis
Jun 2026
Lipid mediators play pivotal roles in regulating skin inflammation and maintaining homeostasis, yet agedependent alterations in these bioactive networks remain poorly characterized. To address this issue, we performed a comprehensive metabololipidomicanalysis combining area-under-the-curve quantification and principal component analysis to profile 24 lipid mediators in young (22.7 ± 5.2 years) versus aged (66.7 ± 7.3 years) human skin explants following PMA-induced inflammatory stress.
Construction of spheroids from melanocytes of different ethnic origins: screening model and variation
Sep 2024
Melanogenesis is a complex porcess, ans its in vitro modeling remains a challenge to develop relevant test suitable for rapid preclinical evaluation of the efficacy of lightening products to modulate human skin pigmentation.
Melanocytes are known to lose their ability to synthesize melanin in monolayer culture, even though the melanin content correlates with the ethnic background of the donors. Tissue engineering is an alternative to 2D culture because the cell behaviors in 3D microenvironment are closer to skin physiology.
We therefore compared the efficacy of 3 assays as high-throughput in vitro systems for skin-lightening drug screening: (i) Monolayer 2D culture of proliferative melanocytes, (ii) Microtissue 3D spheroid of non-proliferative melanocytes, (iii) Epidermal tissue 3D model containing functional melanocytes.
