All publications
Advantages of combining cellulosic polymers and lipids in extruded 3D printing filaments - Part I
ECP - Mar 2025
This study explores the use of 3D printing, specifically fused deposition modeling (FDM), for personalized medicine by combining lipids and cellulosic excipients like hypromellose (HPMC). Hot-melt extrusion (HME) is employed to create filaments, with a focus on balancing processing temperatures and mechanical properties.
Comparing the effect of adding Gelucire® 48/16 and Gelucire® 50/13 in amorphous solid dispersion: a case study with ticagrelor
CRS - Jul 2024
When amorphous solid dispersion (ASD) are produced by hot melt extrusion (HME), the use of a neat polymer requires high process temperatures, and the drug release is not always complete. Adding Gelucire® in the formula is a promising strategy to address these issues.
Advantages of combining polymers and lipids in extrusion processes
PBP - Mar 2024
Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.