All publications
Advantages of combining cellulosic polymers and lipids in extruded 3D printing filaments - Part I
ECP - Mar 2025
This study explores the use of 3D printing, specifically fused deposition modeling (FDM), for personalized medicine by combining lipids and cellulosic excipients like hypromellose (HPMC). Hot-melt extrusion (HME) is employed to create filaments, with a focus on balancing processing temperatures and mechanical properties.
Comparing the effect of adding Gelucire® 48/16 and Gelucire® 50/13 in amorphous solid dispersion: a case study with ticagrelor
CRS - Jul 2024
When amorphous solid dispersion (ASD) are produced by hot melt extrusion (HME), the use of a neat polymer requires high process temperatures, and the drug release is not always complete. Adding Gelucire® in the formula is a promising strategy to address these issues.
Advantages of combining polymers and lipids in extrusion processes
PBP - Mar 2024
Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.
Gelucire® 48/16: a safe wetting agent for tablet. A case study with fenofibrate
CRS Annual Meeting – Montreal (Canada) - Jul 2022
Gelucire 48/16® for Type-IV Lipid Based Formulations and Their In Vitro In Vivo Performance Evaluation
AAPS PharmSci360 – San Antonion (USA) - Nov 2019
A Novel Approach To Prepare Solid Self-microemulsifying Drug Delivery System Without A Solid-phase Carrier Using 3D Printing
CRS Annual Meeting – New York (USA) - Jul 2018
Bioavailable Curcumin – A Type 4 Lipid Based Drug Delivery System Using Gelucire®48/16 As Solid Solubilizer
CRS Annual Meeting – New York (USA) - Jul 2018
The Gelucire® family
Pharma Excipients - 2018
Gelucire 48/16®: A Non-Ionic Solid Surfactant for Solubility Enhancement of Poorly Soluble Drugs
AAPS Annual Meeting & Exposition – San Diego (USA) - Nov 2017