The simplest process for the production of tablets.
It consists of three main steps: powder blending, lubrication, and compression. Atomized lipid excipients are used as lubricants or modified-release agents in direct compression.
Advantages of lipid excipients in direct compression
chemical inertness, preventing incompatibilities with other excipients or drugs
batch-to-batch composition uniformity, ensuring high quality and performance of final product (adequate for QbD development)
Range of functional excipients for direct compression
Lubricants to decrease friction between particles and compression tools
Compritol® 888 ATO—for pharmaceutical tablets
Compritol® HD 5—for water-dispersible tablets
Compritol® 888 ATO—a well-established sustained-release agent with precedence of use and numerous publications demonstrating efficacy
Compritol® 888 ATO: a must-have lubricant
Sustain drug release with Compritol® 888 ATO