Direct compression

The simplest process for the production of tablets. 


It consists of three main steps: powder blending, lubrication, and compression. Atomized lipid excipients are used as lubricants or modified-release agents in direct compression. 

Advantages of lipid excipients in direct compression

  • chemical inertness, preventing incompatibilities with other excipients or drugs 

  • batch-to-batch composition uniformity, ensuring high quality and performance of final product (adequate for QbD development) 

Range of functional excipients for direct compression

  • Compritol® 888 ATO—a well-established sustained-release agent with precedence of use and numerous publications demonstrating efficacy 

Compritol® 888 ATO: a must-have lubricant 

Sustain drug release with Compritol® 888 ATO