A glyceride with a high melting point used as a modified release agent or lubricant in tablets. Can also be used in lipid coating technologies and as lipid carrier for nanoparticles.
Names & synonyms
|USP NF Name
|UNII Code (FDA)
|Preferred Substance Name (FDA)
|Handbook of Pharmaceutical Excipients
Consists of mono-, di- and triesters of behenic acid (C22), the diester fraction being predominant.
Modified release matrix former for tablet. Lubricant for tablet—independent of mixing time and speed. Lipid carrier former for solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC). Coating agent for taste masking and protection of sensitive APIs.
Listed in the European STEP database for excipients in pediatric medicines.
Safety of use is inferred by GRAS status and precedence of use in approved pharmaceutical products.