A thixotropic suspension vehicle for pharmaceutical APIs. Ready-to-use in a cold process for thermosensitive actives in soft gel capsule.
Names & synonyms
|USP NF Name||
Mixture of refined soybean oil USP-NF, glyceryl distearate USP-NF and polyglyceryl-3 dioleate USP-NF
Mixture of refined soybean oil EP, glyceryl distearate EP and polyglyceryl-3 dioleate
|UNII Code (FDA)||
241ATL177A 73071MW2KM XRQ165498B
|Preferred Substance Name (FDA)||
Soybean oil Glyceryl distearate Polyglyceryl-3 oleate
|Handbook of Pharmaceutical Excipients||
Soybean oil Glyceryl palmitostearate
Consists of a mixture of refined soybean oil, glyceryl distearate (C18) and polyglyceryl-3 dioleate (C18:1)
Soybean oil: food grade Glyceryl palmitostearate: FCC, GRAS 21 CFR §184.1329, JSFA
Vehicle to suspend pharmaceutical ingredients in soft gelatin capsule.
Good dispersibility in aqueous fluid.
High drug load achievable.
Thixotropic behavior: can be processed only by mixing—ideal for sensitive actives.
Safety of use is inferred by food additive status and precedence of use.
Main formulation technologies
Soft capsule filling