All publications

Advantages of combining cellulosic polymers and lipids in extruded 3D printing filaments - Part I

  • Poster

ECP - Mar 2025

Philippe Caisse, Ceren Yuece, Veronique Henner-Kulkarni, Elsa Gattefossé

This study explores the use of 3D printing, specifically fused deposition modeling (FDM), for personalized medicine by combining lipids and cellulosic excipients like hypromellose (HPMC). Hot-melt extrusion (HME) is employed to create filaments, with a focus on balancing processing temperatures and mechanical properties.

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Advantages of combining polymers and lipids in extrusion processes

  • Poster

PBP - Mar 2024

Ceren Yüce, Lolie Cheron, Anja Geissler-Fichtner, Elsa Gattefossé

Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.

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Lipids and polymers in pharmaceutical technology: Lifelong companions

  • Scientific publication

International Journal of Pharmaceutics, Volume 558, 10 March 2019, Pages 128-142 - Mar 2019

Juergen Siepmann, Amina Faham, Sophie-Dorothée Clas, Ben J. Boyd, Vincent Jannin, Andreas Bernkop-Schnürch, Hang Zhao, Sébastien Lecommandoux, James C.Evans, Christine Allen, Olivia M. Merkel, Gabriella Costabile, Morgan R. Alexander, Ricky D.Wildman, Cli

This article reviews the uses of lipids and polymers in pharmaceutical applications, alone or in combination, with a main focus on oral administration.

These topics were discussed at the Journées galéniques de Saint-Rémy de Provence in 2018, the Scientific Meeting sponsored by Gattefossé Foundation