All publications

In Vitro In Silico Correlation of Lidocaine HCl Skin Permeation - A Comparative Study of Gel Cream and Bigel formulations

  • Poster

ECP - Mar 2025

Manon Rossano, Delphine Pélisson, Malaury Ducros, Elise Dauphin-Chanard, Philippe Caisse

In this work, the effectiveness of Skin-in-Silico™ software for simulating dermal absorption and permeation of lidocaine hydrochloride in gel, cream, and bi-gel forms was evaluated. By combining in silico predictions with in vitro experiments, we explore the correlation between these methods and their role in optimizing topical drug formulations.

Formulating pharmaceutical topical dosage forms with high level of solvents and minimal quantity of water

  • Poster

PBP - Mar 2024

Delphine Pélisson, Elise Dauphin-Chanard

This poster dives into the formulation of topical dosage forms containing the maximum amount of solvent and the minimum amount of water, while ensuring their stability upon storage.