• Pharmaceuticals

Controlled Release and Bioavailability Enhancement Summit East

Visit Gattefossé at the Controlled Release and Bioavailability Enhancement (CRBE) Summit East and discover new ways to expand your oral formulation toolbox.

Discover how our solutions enable both small and large molecule delivery through improved solubility, permeation enhancement, lymphatic uptake, and food effect mitigation. 

Want to secure time with our team for detailed discussions? Fill out the form below to schedule a meeting.

Lifecycle Management and Reformulation Opportunities for Peptides and Challenging Small Molecules

As pharmaceutical pipelines increasingly yield complex APIs—including poorly permeable small molecules and peptides—first-generation drug products often fall short of the ideal Target Product Profile. Sub-optimal bioavailability, positive food effects, and reliance on parenteral administration present significant hurdles to patient compliance and market success. 

This presentation explores how lipid-based formulations provide a proven, low-risk toolkit for strategic lifecycle management and 505(b)(2) reformulations. By leveraging IID-listed lipid excipients, formulators can mitigate absorption challenges for small molecules, develop specialized dosage forms, and even achieve the “holy grail” of patient-centricity—oral peptide delivery. 

Highlighting real-world case studies and future-facing formulation approaches, this session will demonstrate how lipid excipients enable value-added reformulations that bring new life to existing assets. 

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