All publications
Gelucire 48/16® for Type-IV Lipid Based Formulations and Their In Vitro In Vivo Performance Evaluation
AAPS PharmSci360 – San Antonion (USA) - Nov 2019
In vitro evaluation of leuprolide-containing solid lipid-based nanosuspensions: ability to encapsulate, release, protect and permeate in the gastrointestinal tract
AAPS PharmSci360 – San Antonion (USA) - Nov 2019
In this study the authors obtained solid lipid nanoparticles using high pressure homogeneization, in which leuprolide was included as an ion pair. The nanoparticles were shown to be internalized by Caco-2 and Caco-2/HT29-MTX cell monolayers.
Synergising excipients to boost skin delivery. A case study with lidocaine hydrochloride
Skinforum 2019 Annual Meeting – Reims (France) - Sep 2019
In this study, the authors showed that combining an efficient solubilizer and penetration enhancer achieves a synergic effect which enhances the passive diffusion of LID HCl through the Strat-M membrane in this Franz cell model.
In Vitro Studies Indicate Promising Properties Of Solid Lipid Nanosuspensions for oral peptide delivery
CRS Annual Meeting – Valencia (Spain) - Jul 2019
Understanding The Role Of In Vitro And In Vivo Evaluation Techniques In Determining the Performance of Lipid-Based Formulations
CRS Annual Meeting – Valencia (Spain) - Jul 2019
In this case study using curcuminoids as model drug, the authors show that in vitro lipolysis test is a useful tool to predict in vivo performance
Investigation of Labrasol® ALF as an intestinal permeation enhancer: Ussing chambers and intestinal instillations
Poster presented at Keystone Symposia on Molecular and Cellular Biology – Delivering Therapeutics Across Biological Barriers (E1) - Dublin (Ireland) - May 2019