All publications
Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
AAPS PharmSciTech - Sep 2024
The review examines how hydroalcoholic solvents, especially Transcutol, enhance drug delivery in multi-component formulations. It highlights factors like drug diffusion, solubilization, and skin absorption, focusing on the interaction between drug properties, skin barrier, and formulation for effective (trans)dermal delivery.
Labrafac™ MC60 is an efficacious intestinal permeation enhancer for macromolecules: Comparisons with Labrasol® ALF in ex vivo and in vivo rat studies
International Journal of Pharmaceutics - Jun 2024
In this article, demonstration on how Labrafac™ MC60 acts as a safe intestinal permeation enhancer is given, with insulin as a model molecule. Studies were conducted in vivo and ex vivo, using isolated muscle-stripped rat jejunal and colonic mucosae.