All publications

Size characterization of commercial micelles and microemulsions by Taylor dispersion analysis

• Scientific publication

International Journal of Pharmaceutics, Volume 492, Issues 1–2, Pages 46-54 - Aug 2015

Joseph Chamieh, Florian Davanier, Vincent Jannin, Frédéric Demarne, Hervé Cottet

In vitro lipolysis tests on lipid nanoparticles: comparison between lipase/co-lipase and pancreatic extract.

• Scientific publication

Drug Development and Industrial Pharmacy - Volume 41 - Issue 10 https://doi.org/10.3109/03639045.2014.972412 - 2015

Jannin V, Dellera E Chevrier S, Chavant Y, Voutsinas C, Bonferoni C, Demarne F.

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

• Scientific publication

Pharmaceutical Research volume 32, pages 1279–1287 DOI: 10.1007/s11095-014-1532-y  - Apr 2015

Bakala-N’Goma, J.C., Williams, H.D., Sassene, P., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Müllertz, A., Pouton, C.W., Porter, C.J.H., Carrière, F.

Biorelevant media resistant co-culture model mimicking permeability of human intestine.

• Scientific publication

International Journal of Pharmaceutics, Volume 481, Issues 1–2, Pages 27-36 - Mar 2015

Delphine Antoine, Yann Pellequer, Camille Tempesta, Stefan Lorscheidt, Bernadette Kettel, Lana Tamaddon, Vincent Jannin, Frédéric Demarne, Alf Lamprecht, Arnaud Béduneau

Cell culture models are currently used to predict absorption pattern of new compounds and formulations in the human gastro-intestinal tract (GIT). One major drawback is the lack of relevant apical incubation fluids allowing mimicking luminal conditions in the GIT. Here, we suggest a culture model compatible with biorelevant media, namely Fasted State Simulated Intestinal Fluid (FaSSIF) and Fed State Simulated Intestinal Fluid (FeSSIF).