All publications
Lipid-based nanosuspensions for oral delivery of peptides, a critical review
International Journal of Pharmaceutics, Volume 541, Issues 1–2, Pages 117–135 - Apr 2018
In this review article, the authors describe:
the different techniques used to prepare Solid Lipid Nanoparticles and Nanostructured Lipid Carriers
the methods used to assess the protective effects of the carriers on peptides
the techniques used to measure the permeability enhancement
Evaluation of the digestibility of solid lipid nanoparticles of glyceryl dibehenate produced by two techniques: Ultrasonication and spray-flash evaporation
European Journal of Pharmaceutical Sciences , Volume 111, Pages 91-95 https://doi.org/10.1016/j.ejps.2017.09.049 - Jan 2018
In this study, solid lipid nanoparticles (SLN) of glyceryl dibehenate are produced by two methods and evaluated for digestion using the in vitro lipolysis test.
By ultrasonication, SLN have a mean particle size of 180 nm and showed a limited digestion by lipase.
By spray-flash evaporation, SLN particle size ranges from 235 to 411 nm, depending on process conditions and were not digested by lipase.