All publications

An All-Purpose Vehicle for Low-Energy Capsule Filling

  • Whitepaper

Tablets&Capsules - Apr 2023

Jasmine Musakhanian; Masumi Dave; Elise Dauphin-Chanard

Capsules are perceived as elegant, easy-to-swallow dosage forms, widely used for delivery of nutraceutical and medicinal preparations. Advances in capsule technologies have hugely facilitated the incorporation of liquid, semi-solid, and solid ingredients into capsules. 

LIPID-BASED EXCIPIENTS – Misconceptions About Lipid-Based Drug Delivery

  • Whitepaper

Drug Development & Delivery - Apr 2023

Rollie Fuller and Ron Permutt

Cannabinoid molecules and their love of lipid excipients

  • Whitepaper

Pharmaceuticals & Cosmetic Review - Feb 2022

Gattefossé

DOs and DON’Ts for developing successful SEDDS formulations to enhance API bioavailability

  • Whitepaper

Tablets&Capsules, p.37-39  - Apr 2020

Inayet Ellis

A snapshot of lipid excipients for topical formulations

  • Whitepaper

Pharma Times – Vol. 51 – No. 59 - Sep 2019

Gattefossé

Lipid excipients in pharmaceutical technologies
Nabil FARAH and Joel DENIS

Lipidic excipients in drug delivery for solubility and bioavailability enhancement
Prashantkumar K. PARMAR, Srilaxmi G. RAO, Arvind KK. BANSAL

From exploration of lipids to its exploitation in market: Pharmaceuticals, Nutraceuticals and Herbal
Saurabh ARORA, Abhinav GARG, Karishma KAPOOR

A snapshot of lipid excipients for topical formulations
Renuka TIWARI, Ketkee DESHMUKH, Agnivesh SHRIVASTAVA, Kanchan KOHLI

Strategic lipid-based delivery interventions for enhancing oral bioavailability of BCS II/IV drugs
Teenu SHARMA, Ranjot KAUR, Sumant SAINI, Atul JAIN, Bhupinder SINGH

 Unleashing role of excipients in overcoming formulation challenges
Meenakshi VENKATARAMAN, Megha MARWAH, Mangal NAGARSENKER

Role of lipid excipients in oral sustained release drug delivery systems
Divya JAIN, Namita DESAI

The Gelucire® family

  • Whitepaper

Pharma Excipients  - 2018

Gattefossé

LIPID-BASED DELIVERY – Are Lipid-Based Drug Delivery Systems in Your Formulation Toolbox?

  • Whitepaper

Drug Development & Delivery, Vol. 17, No. 7, p.20-25 - Oct 2017

Dr. Jason LePree

This article reviews the causes of poor bioavailability for drugs. It provides an introduction to lipid-based drug delivery systems, and how the formulation approach can be used to overcome impediments to good bioavailability of therapeutic actives, including poor water solubility, low permeability, and degradation by stomach acid or enzymes in vivo.

Amélioration de la biodisponibilité des substances actives via la formulation [Bioavailability enhancement of active pharmaceutical ingredients through formulation strategies] galénique

  • Whitepaper

STP Pharma Pratiques, Mai-Juin 2017, n°1 - 2017

E Levacher, C Buffangeix, MJ Celadon, I Decorte, P Gestin, J Hecq, F Jego, B Paillard, A Plantefeve, X Thomas

The SFSTP commission on Bioavailability published an article reviewing the formulation strategies to enhance the bioavailability of APIs.

Interestingly this article is both in French and English languages.

Table of content:

I Introduction

II Prerequisites

1 Initial identification and characterization of the active ingredient
1.1 Physico-chemical characteristics
1.2 Impact of physicochemical characteristics on absorption
1.3 Passive diffusion prediction tools
1.4 In silico prediction
2 Biopharmaceutical classifications

III Formulation strategies

1 Prerequisites
2 Techniques for increasing the dissolution rate
3 Solubility enhancement technologies
4 Improving the permeability, oral route

IV Control, assessment, prediction of the bioavailability

1 Physicochemical control methods for the manufacturing intermediates and finished products
2 Assessing and predicting the bioavailability of the formulations

V Alternative strategy: changing the route of administration

VI Conclusion: decision tree