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Gelucire 48/16®: A Versatile Non-Ionic Solid Solubilizer for Tablets of Poorly Water-Soluble Drugs
AAPS PharmSci360 – Washington DC (USA) - Nov 2018
A solid dispersion of ticagrelor and Gelucire® 48/16 is prepared to increase drug solubility . The solid dispersion is converted into tablets. The formulated tablets showed improved dissolution rate compared to the market reference.