All publications
Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
AAPS PharmSciTech - Sep 2024
The review examines how hydroalcoholic solvents, especially Transcutol, enhance drug delivery in multi-component formulations. It highlights factors like drug diffusion, solubilization, and skin absorption, focusing on the interaction between drug properties, skin barrier, and formulation for effective (trans)dermal delivery.
Rheology as a tool for characterizing topical product formulations: impact of solubilizer variation on stability and structure
CRS - Jul 2024
The use of solubilizers in a topical formulation helps solubilization of poorly soluble APIs. Therefore, it is essential to have a formulation chassis that can be modulated to incorporate this quantity of solubilizer. In this poster, the influence of different excipients as solubilizers and their variation on the stability and rheological properties of topical creams is investigated.
Formulating pharmaceutical topical dosage forms with high level of solvents and minimal quantity of water
PBP - Mar 2024
This poster dives into the formulation of topical dosage forms containing the maximum amount of solvent and the minimum amount of water, while ensuring their stability upon storage.