All publications

Process analytical strategies for size monitoring: offline, at-line, online, and inline methods in a top-down nano-manufacturing line

• Scientific publication

Pharmaceutics - May 2025

Christina Glader, Ramona Jeitler, Yan Wang, Remy van Tuijn, Albert Grau-Carbonell, Carolin Tetyczka, Steve Mesite, Philippe Caisse, Johannes Khinast, Eva Roblegg

This study highlights that combining offline, at-line, in-line, and online DLS methods enables thorough monitoring across the entire lipid nanoparticles production process. This integrated approach streamlines operations, supports real-time process adjustments, and ensures dependable quality control both post-production and during storage.

Veterinary soft chews using Gelucire® 50/13 and Precirol® ATO 5. A proof of concept with wet extrusion

• Poster

ECP - Mar 2025

Fleur Guénard, Cécile Morin, Ceren Yuece, Philippe Caisse

This study aims to demonstrate the effectiveness of Gelucire® 50/13, a surfactant, and Precirol® ATO 5, a taste-masking agent, in producing veterinary soft chews using a wet extrusion process. These ingredients enable the development of high-drug load formulations with taste-masking capabilities and customizable drug release profiles, making them ideal for this innovative dosage form.