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Optimizing a wet granulation process to obtain high-dose sustained-release tablets with Compritol® 888 ATO.
Drug Development and Industrial Pharmacy, Volume 41 - Issue 10 https://doi.org/10.3109/03639045.2014.1002410 - Feb 2015
This study demonstrates how a wet granulation with Compritol® 888 is an effective approach to improve material flow and compressibility. High-dose lipid matrix tablets with sustained release profiles were successfully produced.