Peceol™

An oily vehicle used as solubilizer for lipophilic APIs in oral and topical formulations.

Names and synonyms

USP NF Name

Glyceryl monooleate (Type 40)

EP Name

Glycerol mono-oleates (Type 40)

UNII Code (FDA)

4PC054V79P

Preferred Substance Name (FDA)

GLYCERYL OLEATE

Handbook of Pharmaceutical Excipients

Glyceryl monooleate

Chemical description

Consists of mono-, di- and triglycerides of oleic (C18:1) acid, the monoester fraction being predominant

Key characteristics

Product form

Liquid

Viscosity (mPa.s)

220 (20°C)

HLB

1

Main functionalities

Solubilizer for lipophilic APIs and bioavailability enhancer.
Oily vehicle containing long-chain fatty acids (C18:2) for LFCS Type I (oily), Type II (SEDDS), and Type III (SMEDDS), associated with lymphatic absorption.
Oily vehicle for topical formulations.
Safety of use is inferred by GRAS status and precedence of use in approved pharmaceutical products.

Main formulation technologies