A nonionic oil-in-water emulsifier for topical emulsions. It provides excellent emulsion stability with difficult-to-formulate and combination APIs. Provides heat stability and high tolerance over a wide pH range.
Names & synonyms
|USP NF Name
Mono and Diglycerides and Polyoxyl stearate
Glycerol monostearate and macrogol-75 stearate
|UNII Code (FDA)
|Preferred Substance Name (FDA)
GLYCERYL MONOSTEARATE PEG-75 STEARATE
|Handbook of Pharmaceutical Excipients
Glyceryl monostearate Polyoxylethylene stearates
Consists of a mixture of glycerol monostearate and PEG-75 (MW 3500) stearate (C18)
Emulsifier for difficult-to-formulate APIs, API combinations, anhydrous emulsion. Associate with Emulcire™ 61 WL2659 to enhance sensorial and texture properties. Safety of use is inferred by precedence of use in approved pharmaceutical products.