News and hot topics
Revolutionizing oral bioavailability: powdered lipid surfactants for tablets and capsules
Lipid-based excipients are widely recognized to improve API bioavailability by increasing solubility and permeability. Commonly liquid or waxy, they were primarily formulated in liquid dosage forms, whereas their use in oral solid dosage forms remained sporadic. Formulators often perceived lipid-based excipients as difficult to incorporate in their oral solid dosage forms manufacturing processes. Recent developments at Gattefossé opened the path for new powder surfactants, directly processable in tablets or hard capsules.
Lipid-Polymer Synergies: Enhancing Tablet Performance for New Drug Modalities
05 Jun 2026 Reading : 9mn
Discover how lipid excipients can enhance the performance of oral tablet formulations. Learn how common processing techniques such as spray drying and hot melt extrusion can be combined with lipid chemistries to boost drug exposure.
Lifecycle Management and Reformulation Opportunities with Lipid Excipients
06 Avr 2026
Discover how lipid-based drug delivery systems solve complex 505(b)(2) reformulation challenges. Learn proven strategies to mitigate food effect, enable injectable-to-oral switches, and accelerate speed to market for patient-centric therapies.
Oral peptide delivery with lipid-based excipients
In this article, we explore why lipids and peptides are compatible, how lipid based formulations can address key peptide oral delivery challenges, and how Gattefossé supports formulators in this rapidly evolving field.
In the spotlight: spot-on solutions!
Discover how Gattefossé excipients enhance the formulation of spot-on veterinary treatments!
Soft chews, the pet-fect dosage form!
Learn how Gattefossé excipients can be used for this convenient veterinary dosage form!
Transcutol® V, your ally for formulating veterinary medicines
This excipient is a must when it comes to the formulation of veterinary medicines, as it can be used for oral, topical, and parenteral dosage forms.
The basics of intestinal permeation
Improving the oral bioavailability of pharmaceuticals is a challenging task, heavily influenced by the solubility and permeability of the active pharmaceutical ingredient. Intestinal permeation enhancers, such as medium chain fatty acid esters, play a crucial role in this context by facilitating the passage of drugs through the intestinal barrier, thus improving their absorption and therapeutic efficacy.
Harnessing lipids as plasticizers in hot-melt extrusion: a gateway to innovation
Unlocking a new opportunity to use lipid excipients
