Characterization methods

In this section, learn more about the methods used to characterize lipid excipients and formulations based on lipid excipients.

Developing successful lipid-based formulations

Measuring saturation solubility

HPLC vials

Obtaining solubility data in a sufficiently broad range of lipid excipients is the first step towards the development of a lipid-based formulation

Miscibility and dispersability test

Technician behind dissolution bowls

If a single excipient cannot solubilize the entire therapeutic dose, a multi-excipient formulation is developed. It is necessary to determine the excipients ratio.

In vitro lipolysis test

Technician working at a pHstat station

Assessing formulation behaviour during digestion through this in vitro method, allow to discriminate between formulations for further development.

Taylor Dispersion Analysis

Taylor Dispersion Analysis enables to measure the absolute radius of micelles. It has been used  to characterize our self-emulsifyinig excipients.

Taylor dispersion analysis

PIT-deviation method

HLB measurment method by PIT analysis

HLB (hydrophilic lipophilic balance) is a critical parameter used to characterize surfactants. The PIT-deviation method is a fast and accurate method to measure HLB.

Sensorial analysis

A scientific discipline to formulate patient-friendly textures and increase patients' adherence to topical treatments.

technician hands doing a sensory analysis of a topical formula