Publications

Differential profiles of pro-inflammatory and specialized pro-resolving lipid mediators in PMA-treated skin biopsies from young and old donors

• Article scientifique

Journal of Investigative Dermatology - 2018

N. Bechetoille, V. Baillif, A. Lopez-Gaydon, E. Van Goethem, F. Demarne, M. Dubourdeau

The skin immune system is regulated by bioactive lipids that initiate and amplify inflammation but control its efficient ending also called resolution.

Keratinocyte stem cells are more resistant to UVA radiation than their direct progeny

• Article scientifique

PLOS ONE - 2018

Elodie Metral, Nicolas Bechetoille, Frédéric Demarne, Odile Damour, Walid Rachidi

Keratinocyte stem cells, which are responsible for epidermal renewal throughout life, are equipped with an efficient arsenal against several genotoxic agents.

Mitochondrial damage and cytoskeleton reorganization in human dermal fibroblasts exposed to artificial visible light similar to screen-emitted light

• Article scientifique

Journal of Dermatological Science - 2018

Adeline Rascalou, Jérôme Lamartine, Pauline Poydenot, Frédéric Demarne, Nicolas Bechetoille

Artificial visible light induces drastic molecular and cellular changes in normal human fibroblasts.

Harmful effects of screen-emitted artificial visible light in dermis: an additional environmental stress not to be neglected

• Poster

IID - 2018

Adeline Rascalou , Frédéric Demarne PhD, Nicolas Bechetoille PhD

We have investigated the effects of artificial visible light in human dermal fibroblasts and we described a patented plant extract of Withania somnifera root able to protect those skin cells.