Nos publications

In-vitro investigation regarding the effects of Gelucire® 44/14 and Labrasol® ALF on the secretory intestinal transport of P-gp substrates

  • Scientific publication

International Journal of Pharmaceutics, Volume 515, Issues 1–2, Pages 293-299 https://doi.org/10.1016/j.ijpharm.2016.10.012 - déc 2016

Océane Dubray, Vincent Jannin, Fréderic Demarne, Yann Pellequer, Alf Lamprecht, Arnaud Béduneau

Development of self emulsifying lipid formulations of BCS class II drugs with low to medium lipophilicity

  • Scientific publication

International Journal of Pharmaceutics, Volume 495, Issue 1, Pages 385-392 - nov 2015

Vincent Jannin, Stéphanie Chevrier, Matthieu Michenaud, Camille Dumont, Silvia Belotti, Yann Chavant, Fédéric Demarne.

This article describes the work undertaken in Gattefossé R&D labs (St Priest) to develop lipid formulations for low to medium lipophilicity API: piroxicam, nifedipine and curcumin and evaluate the effect of in-vitro digestion on the solubilizing capacity of the formulations.