Nos publications
In Vitro In Silico Correlation of Lidocaine HCl Skin Permeation - A Comparative Study of Gel Cream and Bigel formulations
ECP - mar 2025
In this work, the effectiveness of Skin-in-Silico™ software for simulating dermal absorption and permeation of lidocaine hydrochloride in gel, cream, and bi-gel forms was evaluated. By combining in silico predictions with in vitro experiments, we explore the correlation between these methods and their role in optimizing topical drug formulations.
Rheology as a tool for characterizing topical product formulations: impact of solubilizer variation on stability and structure
CRS - jui 2024
The use of solubilizers in a topical formulation helps solubilization of poorly soluble APIs. Therefore, it is essential to have a formulation chassis that can be modulated to incorporate this quantity of solubilizer. In this poster, the influence of different excipients as solubilizers and their variation on the stability and rheological properties of topical creams is investigated.