Transcutol® HP

Highest-purity solvent and solubilizer for solubility and bioavailability enhancement for oral and alternative routes.

Names and synonyms

USP NF Name

Diethylene glycol monoethyl ether

EP Name

Diethylene glycol monoethyl ether

UNII Code (FDA)

A1A1I8X02B

Preferred Substance Name (FDA)

DIETHYLENE GLYCOL MONOETHYL ETHER

Handbook of Pharmaceutical Excipients

Diethylene glycol monoethyl ether

Chemical description

Consists of highly purified diethylene glycol monoethyl ether

Key characteristics

Product form

Liquid

Viscosity (mPa.s)

4.8 (20°C)

HLB

Not applicable

Main functionalities

Solvent and powerful solubilizer.
Cosolvent in surfactant oral formulations—LFCS Type III (SMEDDS) and Type IV (micellar solutions).
Vehicle in parenteral, nasal, ophthalmic formulations.
Safety of use and low irritancy inferred by numerous toxicological studies and precedence of use in approved pharmaceutical products.