Tefose® 1500

A nonionic oil-in-water emulsifier for topical formulations that provides high stability in topical fluid lotions and light emulsions over a wide pH range.

Names and synonyms

USP NF Name

Mixture of PEG-6 stearate and PEG-32 stearate

EP Name

Pending

UNII Code (FDA)

8LQC57C6B0
33GX5WQC0M

Preferred Substance Name (FDA)

PEG-6 STEARATE
PEG-32 STEARATE

Handbook of Pharmaceutical Excipients

Polyoxylethylene stearates

Chemical description

Consists of a mixture of PEG-6 (MW 300) esters of stearic (C18) acid and PEG-32 (MW 1500) esters of stearic (C18) acid

Key characteristics

Product form

Waxy solid

Melting range (°C)

40.4 –  44.4

HLB

10

Main functionalities

Polyvalent emulsifier compatible with all types of oils and ideal for topical lotions.
Stabilizes and improves sensorial and texture properties.
Safety of use is inferred by precedence of use in approved pharmaceutical products.

Main formulation technologies

Topical lotion and light emulsion.