Suppocire® NAI 25A

Hard fat suppository base optimized for the formulation of analgesics and antipyretics. Confers high mechanical resistance and yields harder suppository units.

Names and synonyms

USP NF Name

Hard fat

EP Name

Hard fat

UNII Code (FDA)

8334LX7S21

Preferred Substance Name (FDA)

Fat, hard

Handbook of Pharmaceutical Excipients

Suppository bases, hard fat

Chemical description

Consists of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant

Key characteristics

Product form

Pellets

Melting range (°C)

33-35

Hydroxyl value (mg KOH/g)

20-30

Main functionalities

Base recrystallizes rapidly and produces harder suppository units with high mechanical resistance.

Main formulation technologies