Suppocire® D

Hard fat suppository base with a very high melting point optimized for APIs that decrease the mass melting point, such as liquid lipophilic APIs.

Names and synonyms

USP NF Name

Hard fat

EP Name

Hard fat

UNII Code (FDA)

8334LX7S21

Preferred Substance Name (FDA)

Fat, hard

Handbook of Pharmaceutical Excipients

Suppository bases, hard fat

Chemical description

Consists of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant

Key characteristics

Product form

Pellets

Melting range (°C)

42-46

Hydroxyl value (mg KOH/g)

20-30

Main functionalities

Versatile base for straightforward formulations recommended for lipophilic APIs.

Main formulation technologies