Suppocire® BS2X

Hard fat suppository base containing polysorbate additive to improve dispersion of hydrophilic APIs in aqueous solutions or hydroalcoholic extracts.

Names and synonyms

USP NF Name

Hard fat

EP Name

Hard fat with additive

UNII Code (FDA)

14BGY2Y3MJ

Preferred Substance Name (FDA)
Handbook of Pharmaceutical Excipients

Suppository bases, hard fat

Chemical description

Consists of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant and containing  polysorbate 65

Key characteristics

Product form

Pellets

Melting range (°C)

35-39

Hydroxyl value (mg KOH/g)

15-25

Main functionalities

Facilitates dispersion of hydrophilic APIs.
Prevents the exudation of APIs.

Main formulation technologies