Suppocire® AGP

Hard fat suppository base with emulsifier to improve dispersion of hydrophilic APIs, recommended for formulation of glycerin suppositories.

Names and synonyms

USP NF Name

Hard fat EP/NF/JPE with Glycerol monostearate EP/NF and PEG-75 stearate NF/JPE

EP Name

Hard fat EP/NF/JPE with Glycerol monostearate EP/NF and PEG-75 stearate NF/JPE

UNII Code (FDA)

8334LX7S21 230OU9XXE4 OT38R0N74H

Preferred Substance Name (FDA)

FAT, HARD GLYCERYL MONOSTEARATE PEG-75 STEARATE

Handbook of Pharmaceutical Excipients

Suppository bases, hard fat

Chemical description

Consists of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant and containing glycerol monostearate (C18) and PEG-75 (MW 3500) stearate (C18)

Key characteristics

Product form

Pellets

Melting range (°C)

34.5 – 37.5

Hydroxyl value (mg KOH/g)

40 – 50

Main functionalities

Optimized base for hydrophilic APIs (glycerin), plant extracts, Traditional Chinese Medicines.

Main formulation technologies