A nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.
Consists of polyglyceryl-3 esters of oelic acid (C18:1), the diester fraction being predominant.
Solubilizer for poorly-soluble APIs and bioavailability enhancer.
Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations.
Solubilizer and cosurfactant for microemulsion in topical formulations.
Safety of use is inferred by precedence of use in approved pharmaceutical products.
Self-emulsifying lipid formulation for oral applications.
Topical emulgel, microemulsion, and foam.