A glyceride with an intermediate melting point used as a lipidic vehicle and modified release agent.
Names & synonyms
| USP NF Name | Mono and Diglycerides |
|---|---|
| EP Name | Glycerol Monostearate 40-55 (Type I) |
| UNII Code (FDA) | KC98RO82HJ |
| Preferred Substance Name (FDA) | Glyceryl Monostearate |
| Handbook of Pharmaceutical Excipients | Glyceryl Monostearate |
| Chemical description | Consists of mono-, di- and triesters of palmitic (C16) and stearic (C18) acids |
Key characteristics
| Product form | Pellets |
|---|---|
| Melting range (°C) | 54 - 64 |
| HLB | 3 |
Main functionnalities
Modified release matrix former for capsule. Coating agent for taste masking. Consistency agent. Safety of use is inferred by GRAS status and precedence of use in approved pharmaceutical products.
Main formulation technologies
Melt processes: granulation, coating, capsule molding. Consistency agent for several topical dosage forms.
Resources
Technical documentation
Associated content
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