Publications on solid SMEDDS

List of Gattefossé publications on solid SMEDDS.

Evaluation of spray-congealing to obtain a solid SEDDS

Trung Quan TRAN, Odile CHAMBIN, Vincent JANNIN, Dominique CHAMPION, Rémi SAUREL, Philippe CAYOT

Poster ADRITELF / APGI 2018

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A Novel Approach To Prepare Solid Self-microemulsifying Drug Delivery System Without A Solid-phase Carrier Using 3D Printing

KapilkumarVithani, Alvaro Goyanes, Vincent Jannin, Simon Gaisford, Ben Boyd

CRS 2018 poster

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Solubilisation behaviour of poorly water-soluble drugs during digestion of solid SMEDDS

Kapilkumar Vithani, Adrian Hawley, Vincent Jannin, Colin Pouton, Ben J. Boyd

European Journal of Pharmaceutics and Biopharmaceutics, Volume 130, September 2018, Pages 236-246

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Inclusion of digestible surfactants in solid SMEDDS formulation removes lag time and influences the formation of structured particles during digestion

Kapilkumar Vithani, Adrian Hawley, Vincent Jannin, Colin Pouton, Ben J. Boyd

The AAPS Journal, Vol. 19, No. 3, May 2017
DOI: 10.1208/s12248-016-0036-6

The objective of this study is to evaluate how solid self-microemulsifying drug delivery systems (SMEDDS) behave during digestion. SMEDDS containing Gelucire® 44/14 and surfactants were prepared and their dispersion and digestion behaviors were studied using an in vitro lipolysis model, coupled with small-angle X-ray scattering (SAXS) to determine the formed colloidal structures during digestion in real time.

The study shows that the lipid to surfactant ratio has a significant effect on the kinetics of digestion and an optimum ratio is prerequisite to develop rapidly digestible solid SMEDDS system. 

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Solid State Structural Aspects of Solid Self-microemulsifying Drug Delivery Systems (sSMEDDS) during Digestion

Kapilkumar Vithani, Vincent Jannin, Colin Pouton, Ben J. Boyd

Poster AAPS 2016

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Solidification of liquid self-emulsifying lipid formulations by loading on solid mesoporous carriers

Vincent Jannin; Stéphanie Chevrier; Cédric Miolane; Margaux Metin; Hamza Benhaddou; Yann Chavant; Fred Monsuur; Frédéric Demarne

AAPS 2016

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Interest of carriers for the development of solid self-emulsifying drug delivery systems


Poster PBP 2006

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