Publications on Labrasol®

Publications on Labrasol®

Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies

Fiona Mc Cartney, Vincent Jannin, Stéphanie Chevrier, Hakime Boulghobra, Delyan R. Hristov, Nicolas Ritter, Cédric Miolane, Yann Chavant, Frédéric Demarne, David J. Brayden

In this study Labrasol® ALFwas investigated as an intestinal permeation enhancer in isolated rat colonic mucosae in Ussing chamber and in rat in situ intestinal instillations.

Labrasol® ALF (4 and 8 mg/mL) enhanced the transport of the paracellular markers  across colonic mucosae. The enhancement was non-damaging, transient, and molecular weight-dependent.

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Investigation of Labrasol® ALF as an intestinal permeation enhancer: Ussing chambers and intestinal instillations

Fiona McCartney, Vincent Jannin and David J. Brayden
 
Poster presented at Keystone Symposia on Molecular and Cellular Biology – Delivering Therapeutics Across Biological Barriers (E1)
Dublin (Ireland) – May 2019
 

Labrasol® is an efficacious non-damaging intestinal permeation enhancer in isolated rat intestinal mucosae

Fiona McCartney, Vincent Jannin and David J. Brayden

CRS 2018 poster

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