Publications on lipid-based formulations development
A Systematic Approach to Lipid-Based Formulation Development for a Poorly Soluble API, Fenofibrate
Masumi Dave, M.S., Jason Le Pree, Ph.D., R.Ph.
AAPS 2017
Establishment of a binary phase diagrams database for the development of self-emulsifying lipid-based formulations
Jannin, Vincent; Benhaddou, Hamza; Dumont, Camille; Chevrier, Stéphanie; Chavant, Yann; Demarne, Frédéric
AAPS 2014
Self-formulation protocol: Part I: Solubility determination in liquid and solid excipients
Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013).
AAPS Annual Meeting and Exposition. San Antonio, 2013.
Solubility screening is detailed in both liquid and (semi) solid excipients, to select excipients with highest solubilizing capacity.
Self-formulation protocol: Part II: excipient selection, diagram design and selection of prototype formulations.
Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013)
AAPS Annual Meeting and Exposition. San Antonio, 2013.
Dispersion test and ternary diagramming are detailed, to determine the excipient ratios and prototype formulations
Self-formulation protocol: Part III: impact of lipolysis on prototype formulations.
Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013)
AAPS Annual Meeting and Exposition. San Antonio, 2013.
Lipolysis test is used to determine the capacity of prototype formulations to maintain drug in solubilized state.
