Publications on lipid-based formulations development

List of Gattefossé publications on lipid-based formulation development

A Systematic Approach to Lipid-Based Formulation Development for a Poorly Soluble API, Fenofibrate

Masumi Dave, M.S., Jason Le Pree, Ph.D., R.Ph.

AAPS 2017

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Establishment of a binary phase diagrams database for the development of self-emulsifying lipid-based formulations

Jannin, Vincent; Benhaddou, Hamza; Dumont, Camille; Chevrier, Stéphanie; Chavant, Yann; Demarne, Frédéric

AAPS 2014

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Self-formulation protocol: Part I: Solubility determination in liquid and solid excipients

Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013).
AAPS Annual Meeting and Exposition. San Antonio, 2013.

Solubility screening is detailed in both liquid and (semi) solid excipients, to select excipients with highest solubilizing capacity.

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Self-formulation protocol: Part II: excipient selection, diagram design and selection of prototype formulations.

Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013)
AAPS Annual Meeting and Exposition. San Antonio, 2013.

Dispersion test and ternary diagramming are detailed, to determine the excipient ratios and prototype formulations

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Self-formulation protocol: Part III: impact of lipolysis on prototype formulations.

Jannin, Vincent; Michenaud, Mathieu; Belotti, S.; André, C.; Chevrier, Stéphanie; Chavant, Yann et al. (2013)
AAPS Annual Meeting and Exposition. San Antonio, 2013.

Lipolysis test is used to determine the capacity of prototype formulations to maintain drug in solubilized state.

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