Poor solubility, poor permeability, and pre-systemic elimination are factors that can limit absorption of somedrugs. Lipid excipients have the capability to overcome these hurdles and enhance oral bioavailability throughdifferent mechanisms.
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How to develop lipid-based formulation?
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An optimized LBF enables solubilization of the entire therapeutic dose andmaintains the drug in solubilized state throughout the digestion process.
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To speed up LBF development, we have produced tools to guide you at each stageof development:
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1 – methods for saturation solubility screening
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2 – database of solubility of drugs in common pharmaceutical excipients
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3 – methods for miscibility and dispersability testing
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4 – miscibility table
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5 – in vitro lipolysis procedure
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6 – guideline for preclinical studies
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What are the different types of lipid-based formulations?
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Depending on their composition, LBF exhibit different in vivo behaviors. They typically consist of biocompatible excipients falling into four main categories: oils, low-HLB surfactants, high HLB surfactants and co-solvents. To facilitate their identification, Poutonet al. introduced the Lipid Formulation Classification System based on the composition, size of the droplets generated after the dispersion of the formulation in aqueous media, and the impact of natural lipid digestion process on the in vivo performance of the formulation classes.
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What functional excipients for oral bioavailability enhancement do Gattefossé deliver?
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Our range of functional excipients includes oils, low HLB surfactants, high HLB surfactants and solvents. They can be combined to formulate all types of lipid-based formulations
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What are self-emulsifying formulations?
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Self-emulsifying lipid formulations form emulsions upon contact with aqueous fluids without the need for mechanical or thermal energy.The size of the dispersion depends on the composition of excipients in the formulation.
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How to use lipid excipients and lipid-based formulations in early stage development?
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A vehicle or formula intended for preclinical studies must allow adequate administration of the test compound with little or no effect on the test species. The vehicle or formulation must be suitable for the intended route of administration, maintain the stability of the active ingredient, and preferably, maximize the systemic bioavailability of the drug. Lipid excipients provide a solution to these challenges and have proven utility in preclinical studies. Further information is available from Gattefossé guideline
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Founded in Lyon, France, in 1880, Gattefossé is a leading provider of specialty ingredients and formulation solutions for the beauty and health care industries worldwide. Our history is built on our founders’ deep commitment to sustainability, innovation, and service. Specialists in lipid chemistry and plant extraction, we create effective natural actives and functional lipid excipients. We work diligently to guarantee the quality and reliability of our ingredients while providing our customers with all the support and resources they need to make successful products that address global consumers’ demands.
For nearly 140 years, our strategy of continuous investment in research, development, and applications has driven our capacity to innovate. Gattefossé customers benefit from the company’s unique know-how and ability to stay one step ahead of market trends in the personal care and pharmaceutical sectors.
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A partially anionic oil-in-water emulsifier for topical formulations. It enables the formulation of anhydrous emulsions for hydrosensitive APIs and emulsions with solvents or large amount of oily phase.
\n","names_kv":[{"keys":"USP NF Name","value":"
Mixture of Triceteareth-4 phosphate and Ethylene glycol palmitostearate and Diethylene glycol palmitostearate
\n"},{"keys":"EP Name","value":"
Mixture of Triceteareth-4 phosphate and Ethylene glycol palmitostearate and Diethylene glycol palmitostearate
\n"},{"keys":"UNII Code (FDA)","value":"
/ 0324G66D0E 94YQ11Y95F
\n"},{"keys":"Preferred Substance Name (FDA)","value":"
/ GLYCOL STEARATE PEG-2 STEARATE
\n"},{"keys":"Handbook of Pharmaceutical Excipients","value":"
Ethylene Glycol Palmitostearate
\n"},{"keys":"Chemical description","value":"
Consits of a mixture of triceteareth-4 phosphate, ethylene glycol esters of palmitic (C16) end stearic (C18) acids and diethylene glycol esters of palmitic (C16) end stearic (C18) acids
Emulsifier for anhydrous topical formulations. Emulsifier for difficult-to-formulate emulsions (solvents and large oily phase). Stabilizes and improves sensorial and texture properties. Safety of use is inferred by precedence of use in approved pharmaceutical products.
\n","main_formulation_technologies":"
Topical emulsion and foam (with aerosol). One-pot formulation process can facilitate manufacturing.
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Critical Criteria for Assessing the Permeation Performance of Topical Formulas on Animal Skin: Standardization of IVPT Protocols
\n
E. Dauphin-Chanard; A. Forest; C. Deleglise; D. Hoste; P. Caisse
\n
Poster PBP 2022
\n
To assess the performance of dermal/transdermal formulation, in vitro permeation test (IVPT) with Franz cells is a reliable, reproducible, and widely used technique1. Due to its histological similarity, pig skin is a common model used as an alternative to human skin2. However, careful consideration should be given to the pig skin preparation, as both permeability and lag time can be greatly affected. The main variation sources are pig skin storage time, skin integrity and thickness, sample quantity and methodology to apply the formulation on the membrane. This study aims to investigate the critical parameters affecting the data’s accuracy by evaluating the permeation of a lidocaine hydrochloride-based gel (LID HCl) on pig skin.
Investigation of the permeation enhancer strategy on benzoylaconitine transdermal patch: the relationship between transdermal enhancement strength and physicochemical properties of permeation enhancer
In this study several permeation enhancers are evaluated for their ability to permeate high molecular weight benzoylaconitine. The results showed that Plurol® Oleique CC 497 enabled the highest permeation. FT-IR studies demonstrated that the enhancer had strong interactions with the Stratum corneum, both in the hydrophilic and lipophilic regions. The optimized patch formulation showed excellent analgesic and antiinflammatory effect.
Synergising excipients to boost skin delivery. A case study with lidocaine hydrochloride
\n
E. Dauphin-Chanard; A. Forest; C. Deleglise; M. Ducros; D. Marchaud
\n
Poster Skin Forum 2019
\n
In this study the authors showed that combining an efficient solubilizer and penetration enhancer achieves a synergic effect which enhances the passive diffusion of LID HCl through the Strat-M membrane in this Franz cell model.
Development of a daphnetin transdermal patch using chemical enhancer strategy: insights of the enhancement effect of Transcutol P and the assessment of pharmacodynamics.
\n
Shen M, Liu C, Wan X, Farah N, Fang L.
\n
Drug Dev Ind Pharm. 2018 Oct;44(10):1642-1649. doi: 10.1080/03639045.2018.1483391. Epub 2018 Jul 2.
\n
A patch for transdermal delivery of daphnetin was developped using Transcutol® P as permeation enhancer.
\n
The study showed:
\n
\n
10% Transcutol® P led to a significant increase in drug release from the patch.
\n
Patch exhibited analgesic and anti-inflammatory activity
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Symbols of perfect beauty, Japanese women are renowned for the quality of their skin and consider in depth moisture as the secret to skin perfection.
\n
\n
All over the world, women are inspired by the Japanese ideal. The desire to obtain healthy and pure skin represents a new beauty paradigm where beauty is expressed without artifices and the skin must reflect its perfection naturally.
\n
\n
Guided by this new beauty philosophy, Gattefossé developed Gatuline® Renew. It kick-starts the cell renewal process and strengthens the barrier function. The skin is visibly more hydrated, softer and smoother both to the eyes and to the touch. Reflecting light better, the skin reveals all its natural beauty.
A natural extract of handpicked Japanese cedar buds, Gatuline® Renew is rich in energetic phytochemicals that stimulate epidermal renewal.
\n
\n
Native to Japan, the Japanese cedar (Cryptomeria japonica) has been transplanted to the Reunion Island. The plant thrives on the island, where Gattefossé sources the buds used in Gatuline® Renew.
\n
\n
\n
\n
A responsible sourcing: Japanese cedar buds are picked by hand. To ensure the longevity of the trees, only their lower branches are cut.
Boosts all essential steps of epidermis renewal and strengthens stratum corneum
\n
Improves the desquamation
\n
Restores a functional skin barrier
\n
Promotes proper water homeostasis
\n
Enhances skin surface aspect
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Acts throughout the epidermis, from the basal layer to surface corneocytes
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Favors hydration from within
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Prevents dehydration
\n
Smoothes the skin, making it softer, more supple and comfortable
\n
Enhances global skin quality and appearance
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Adapted to sensitive skin (clinical test under dermatological control)
A glyceride with an intermediate melting point used as a matrix agent for sensitive APIs and a viscosity-increasing agent in oral and topical formulations.
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Hard fat
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Hard fat
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8334LX7S21
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FAT, HARD
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/
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Consists of mono-, di- and triglyceride esters of fatty acids (C8 to C18), the triester fraction being predominant
Matrix-forming agent for protection of APIs sensitive to oxidation, humidity, or light. Consistency agent in oral and topical formulations. Safety of use is inferred by precedence of use in approved pharmaceutical products.
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Agent de texture naturel et durable, Lipocire™ A SG donne du corps aux formules cosmétiques et leur confère un toucher plus onctueux, ultra fondant.
\n
Une expérience sensorielle unique dans de nombreuses applications soin et maquillage.
Beurre végétal texturant, Lipocire™ A SG est issu de l’hydrogénation et de l’inter-estérification d’huiles de palme et de palmiste, extraites des fruits et des graines du palmier à huile. Relipidants et nourrissants, ces lipides filmogènes présentent une excellente affinité avec la peau et permettent de reconstituer le film protecteur hydrolipidique. Ils apportent douceur et confort à la peau et aux formulations.
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Gattefossé n’utilise que des huiles de palme et de palmiste certifiées RSPO Segregated (SG) (Roundtable on Sustainable Palm Oil). Cette certification garantit que les huiles proviennent exclusivement de plantations gérées durablement.
\n
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Le fruit du palmier a la peau rouge foncé et la chair jaune-orange, il est particulièrement riche en éléments nutritifs. La pulpe du fruit et l’amande dans son noyau ont tous deux une teneur élevée en triglycérides (> 50%).
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Autres grades disponibles :
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Lipocire ™ CM SG a un point de fusion légèrement supérieur et est préconisé pour les formulations de plus grande rigidité : par exemple, sticks ou poudres pressées.
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Lipocire ™ DM SG a un point de fusion supérieur aux deux autres grades. Il est conseillé de l’utiliser pour les formulations avec une solidité encore plus grande, comme les crayons de maquillage.
Maquillage : mascaras, rouges à lèvres, brillant à lèvres, bâtons, eye-liner, ombres à paupières, rougeurs, poudres en vrac
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An incredible texture for this balm, well-adapted for massage.
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11 am ET - 12 pm ET","location":"Online","type":"","description":"Join us with for a one-hour webinar where the speakers delve into guidelines for the design, characterization and differentiation of SEDDS and SNEEDS formulation systems to pick a prototype for preclinical or clinical trials.","button_label":"Register","image":{"id":27364,"alt":"","title":"GettyImages-1210343139-min","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min.jpg","width":3840,"height":2160,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-300x169.jpg","medium-width":300,"medium-height":169,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-768x432.jpg","medium_large-width":474,"medium_large-height":267,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-1024x576.jpg","large-width":474,"large-height":267,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-1210343139-min-1038x576.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":576}},"link":"https://register.gotowebinar.com/register/674510124274382348"},{"section":"pharmaceuticals","zone":"europe","title":"PBP","date":"March 28-31, 2022 ","location":"Rotterdam","type":"Booth 43","description":"13th World Meeting \r\non Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology \r\n28 - 31 March 2022 | Rotterdam, The Netherlands","button_label":"Register","image":{"id":26746,"alt":"","title":"PBP WORLD MEETING","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING.jpg","width":409,"height":384,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING-300x282.jpg","medium-width":300,"medium-height":282,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING.jpg","medium_large-width":409,"medium_large-height":384,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING.jpg","large-width":409,"large-height":384,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING-409x372.jpg","post-thumbnail-width":409,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PBP-WORLD-MEETING.jpg","twentyfourteen-full-width-width":409,"twentyfourteen-full-width-height":384}},"link":"https://www.worldmeeting.org/home/registration/"},{"section":"pharmaceuticals","zone":"europe","title":"3D printing: One step forward to personalized medicines","date":"April 7, 2022 - 10 am CET - 5 pm CET","location":"Online","type":"","description":"In this webinar, the possibility of combining polymers and lipid excipients to develop 3D printed tablets is demonstrated. The potential to use this technology to develop multicompartment tablets for polypharmacy is highlighted. \r\nThe polymer (PVOH or PLA) is used to design the scaffold, while the lipid self-emulsifying formulations - based on Gelucire® 44/14 or Gelucire® 48/16 - are used to prepare the content, including different model drugs. \r\nThis study demonstrates the feasibility of using 3D printing and this dual polymer/lipid system to develop personalized medicines.","button_label":"Register","image":{"id":26519,"alt":"","title":"EVENT WEBINAIRE","caption":"","description":"","mime_type":"image/png","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","width":266,"height":232,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE-150x150.png","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","medium-width":266,"medium-height":232,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","medium_large-width":266,"medium_large-height":232,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","large-width":266,"large-height":232,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","post-thumbnail-width":266,"post-thumbnail-height":232,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/EVENT-WEBINAIRE.png","twentyfourteen-full-width-width":266,"twentyfourteen-full-width-height":232}},"link":"https://attendee.gotowebinar.com/rt/1736929725888704272?source=Website"},{"section":"personal_care","zone":"europe","title":"In-Cosmetics Global ","date":"5-7 Avril, 2022","location":"Paris, Porte de Versaille","type":"M50","description":"Gattefossé sera présent à In-Cosmetics Global au stand M50","button_label":"Know more","image":{"id":25834,"alt":"","title":"In-Cos Global 2022","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022.jpg","width":432,"height":312,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022-300x217.jpg","medium-width":300,"medium-height":217,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022.jpg","medium_large-width":432,"medium_large-height":312,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022.jpg","large-width":432,"large-height":312,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022.jpg","post-thumbnail-width":432,"post-thumbnail-height":312,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/In-Cos-Global-2022.jpg","twentyfourteen-full-width-width":432,"twentyfourteen-full-width-height":312}},"link":"https://www.in-cosmetics.com/global/en-gb.html"},{"section":"pharmaceuticals","zone":"europe","title":"Transcending transdermal delivery joined webinar Teledyne-Gattefossé","date":"November 30 and December 2nd, 2021 ","location":"webinar","type":"online","description":"Dermal drug delivery is very challenging, and numerous strategies have been developed to overcome the skin barrier. This webinar will demonstrate the importance of formulation on skin delivery, with a strong focus on solubilizers and permeation/ penetration enhancers. The use of Franz cells diffusion system to assess the formulations will be described with detailed information on the methods.","button_label":"Register","image":{"id":25428,"alt":"","title":"LABO-148","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148.jpg","width":800,"height":799,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148-768x767.jpg","medium_large-width":474,"medium_large-height":473,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148.jpg","large-width":474,"large-height":473,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-148-800x576.jpg","twentyfourteen-full-width-width":800,"twentyfourteen-full-width-height":576}},"link":"https://attendee.gotowebinar.com/rt/3820159011397760780?source=GF+website"},{"section":"personal_care","zone":"europe","title":"SCS Formulate","date":"16-17 Novembre 2021","location":"Ricoh Arena, Coventry, UK","type":"523","description":"","button_label":"Know more","image":{"id":25367,"alt":"","title":"scs formulate","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate.jpg","width":634,"height":355,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate-300x168.jpg","medium-width":300,"medium-height":168,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate.jpg","medium_large-width":474,"medium_large-height":265,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate.jpg","large-width":474,"large-height":265,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate.jpg","post-thumbnail-width":634,"post-thumbnail-height":355,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/scs-formulate.jpg","twentyfourteen-full-width-width":634,"twentyfourteen-full-width-height":355}},"link":"https://www.scsformulate.co.uk/"},{"section":"personal_care","zone":"america","title":"New York Suppliers' Day","date":"10-12 Novembre, 2021","location":"New York, Etats-Unis","type":"317","description":"L'événement aura lieu les 10 et 11 novembre au Javits Center de New York. \r\net le 12 novembre, il s'agira d'une journée virtuelle.","button_label":"Know more","image":{"id":25279,"alt":"","title":"NYSCC 2","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2.jpg","width":689,"height":628,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2-300x273.jpg","medium-width":300,"medium-height":273,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2.jpg","medium_large-width":474,"medium_large-height":432,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2.jpg","large-width":474,"large-height":432,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/NYSCC-2-689x576.jpg","twentyfourteen-full-width-width":689,"twentyfourteen-full-width-height":576}},"link":"https://nyscc.org/suppliers-day/"},{"section":"personal_care","zone":"asia_pacific","title":"PCHi, Sommet Technologique","date":"26-27 Octobre, 2021","location":"Yinlong Hall 2, Hôtel Le Méridien, Shanghai, Chine","type":"","description":"Le séminaire aura lieu le 26 Octobre de 13h30 à 17h30. \r\nVoici les sujets qui seront présentés : \r\n- Discours d'ouverture comprenant une présentation rapide de Gattefossé par Rain Shen, Responsable Marketing Cosmétique chez Gattefossé Chine. \r\n- Présentation de la technologie d'émulsification et des tendances de développement en cosmétique par le Professeur Zhang de l'Institut de Technologie de Shanghai. \r\n- De la création de l'ingrédient au développement de la formule : comment l'expertise sensorielle soutient la texture cosmétique ? Vidéo de Vincent Hubiche, Responsable Laboratoires d'Applications Cosmétique chez Gattefossé. \r\n- Comment créer naturellement des émulsions ? Présenté par Angel Li, Responsable Technique Cosmétique chez Gattefossé Chine. \r\n- Les tendances de la cosmétique naturelle (de la cosmétique solide à la biodégradabilité), présenté par Julia Kang, en charge du Marketing Cosmétique chez Gattefossé Chine.","button_label":"Know more","image":{"id":25272,"alt":"","title":"PCHi technology summit","caption":"","description":"","mime_type":"image/png","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit.png","width":792,"height":661,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit-150x150.png","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit-300x250.png","medium-width":300,"medium-height":250,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit-768x641.png","medium_large-width":474,"medium_large-height":396,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit.png","large-width":474,"large-height":396,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit-672x372.png","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/PCHi-technology-summit-792x576.png","twentyfourteen-full-width-width":792,"twentyfourteen-full-width-height":576}},"link":"https://intranet.gattefosse.com/event/pchi-technology-summit/id/419"},{"section":"pharmaceuticals","zone":"europe","title":"CPhI worlwide® 2021 ","date":"October 25 - November 19, 2021","location":"Online Conference & Networking","type":"","description":"CPhI worlwide® brings the global pharma industry together - from APIs, machinery and packaging to outsourcing and biopharmaceuticals. CPhI worlwide® 2021 will be a hybrid event: an Online Conference & Networking session from October 25 to November 19, and an in-person event from November 9 to November 11 in Milano, Italy. \r\n \r\nThis year, Gattefossé is going digital and will exhibit online and will present a large range of novelties! ","button_label":"Register","image":{"id":14286,"alt":"","title":"cphi-worldwide","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","width":266,"height":232,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","medium-width":266,"medium-height":232,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","medium_large-width":266,"medium_large-height":232,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","large-width":266,"large-height":232,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","post-thumbnail-width":266,"post-thumbnail-height":232,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/cphi-worldwide.jpg","twentyfourteen-full-width-width":266,"twentyfourteen-full-width-height":232}},"link":"https://www.cphi.com/europe/en/home.html"},{"section":"personal_care","zone":"europe","title":"Cosmetorium ","date":"20-21 Octobre, 2021","location":"Barcelone, Espagne","type":"256","description":"Découvrez les dernières tendances, innovations et ingrédients en matière de cosmétiques. \r\n \r\nElisa López Rivas, Directrice Marketing et Support Technique chez Gattefossé Espagne prendra la parole le 20 octobre à 11 heures pour une présentation intitulée "Ingrédients cosmétiques : à la recherche d'un avenir durable". Celle-ci portera sur la durabilité des cosmétiques et son importance. Elisa présentera également la politique et les actions mises en place chez Gattefossé pour améliorer la durabilité de ses ingrédients. \r\n \r\nDurant ces 2 jours de salon, nous ferons également la promotion d’ EleVastinTM , notre dernier actif qui renforce l'élasticité de la peau et lutte contre l’affaissement cutané induit par la gravité. \r\n","button_label":"Know more","image":{"id":25261,"alt":"","title":"Cosmetorium","caption":"","description":"","mime_type":"image/png","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium.png","width":305,"height":279,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium-150x150.png","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium-300x274.png","medium-width":300,"medium-height":274,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium.png","medium_large-width":305,"medium_large-height":279,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium.png","large-width":305,"large-height":279,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium.png","post-thumbnail-width":305,"post-thumbnail-height":279,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Cosmetorium.png","twentyfourteen-full-width-width":305,"twentyfourteen-full-width-height":279}},"link":"https://www.cosmetorium.es/en/"},{"section":"pharmaceuticals","zone":"america","title":" AAPS 2021 PharmSci 360","date":"17-20 Octobre, 2021","location":"Online","type":"","description":""The American Association of Pharmaceutical Scientists" (AAPS) organise l'AAPS 2021 PharmSci 360.","button_label":"Know more","image":{"id":14281,"alt":"","title":"aaps-pharma","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","width":266,"height":232,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","medium-width":266,"medium-height":232,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","medium_large-width":266,"medium_large-height":232,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","large-width":266,"large-height":232,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","post-thumbnail-width":266,"post-thumbnail-height":232,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/aaps-pharma.jpg","twentyfourteen-full-width-width":266,"twentyfourteen-full-width-height":232}},"link":"https://www.aaps.org/pharmsci/annual-meeting"},{"section":"pharmaceuticals","zone":"america","title":"The 12th Annual Charles I. 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The conference theme this year is “Advanced Delivery Science”, which reflects our focus on cutting-edge research and innovation across our strong discipline that will keep you up-to-date with new science and inspire new ideas.","button_label":"Register","image":{"id":27480,"alt":"","title":"Logo CRS","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS.jpg","width":395,"height":393,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS-300x298.jpg","medium-width":300,"medium-height":298,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS.jpg","medium_large-width":395,"medium_large-height":393,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS.jpg","large-width":395,"large-height":393,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS-395x372.jpg","post-thumbnail-width":395,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/Logo-CRS.jpg","twentyfourteen-full-width-width":395,"twentyfourteen-full-width-height":393}},"link":"https://www.edgereg.net/er/Registration/StepRegInfo.jsp?ActivityID=39614&StepNumber=1&v=ODk3NTRmMTAtODI3YS00ODY5LTg3YTgtY2Y4NTM1MmMxY2Yy"},{"section":"pharmaceuticals","zone":"europe","title":"Introduction to oral BAE using lipid excipients Part III: Step-by-step development of successful lipid-based formulations","date":"July 7, 2022 - 8:30 am CET ","location":"Online ","type":"","description":"Join us to the third part of our webinar series "Introduction to oral bioavailability enhancement using lipid excipients". This webinar series will give junior formulators key information to understand how LBF address oral bioavailability issues. \r\nIn this third webinar, the methodology to develop optimized lipid-based formulations will be explained. \r\n","button_label":"Register","image":{"id":27449,"alt":"","title":"GettyImages-664495228-min","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min.jpg","width":3087,"height":3083,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-768x767.jpg","medium_large-width":474,"medium_large-height":473,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-1024x1024.jpg","large-width":474,"large-height":474,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-1038x576.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":576}},"link":"https://attendee.gotowebinar.com/register/1396133900118438160?source=WEB"},{"section":"pharmaceuticals","zone":"europe","title":"Introduction to oral BAE using lipid excipients Part II: Overview of Gattefossé excipients for oral bioavailability enhancement","date":"July 6, 2022 - 8:30 am CET ","location":"Online","type":"","description":"Join us to the second part of our webinar series "Introduction to oral bioavailability enhancement using lipid excipients". 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This webinar series will give junior formulators key information to understand how LBF address oral bioavailability issues. \r\nIn this third webinar, the methodology to develop optimized lipid-based formulations will be explained. \r\n","button_label":"Register","image":{"id":27449,"alt":"","title":"GettyImages-664495228-min","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min.jpg","width":3087,"height":3083,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-768x767.jpg","medium_large-width":474,"medium_large-height":473,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-1024x1024.jpg","large-width":474,"large-height":474,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/GettyImages-664495228-min-1038x576.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":576}},"link":"https://attendee.gotowebinar.com/register/1396133900118438160?source=WEB"},{"section":"pharmaceuticals","zone":"europe","title":"Introduction to oral BAE using lipid excipients Part II: Overview of Gattefossé excipients for oral bioavailability enhancement","date":"July 6, 2022 - 8:30 am CET ","location":"Online","type":"","description":"Join us to the second part of our webinar series "Introduction to oral bioavailability enhancement using lipid excipients". This webinar series will give junior formulators key information to understand how LBF address oral bioavailability issues. \r\nIn this second webinar, the full range of Gattefossé excipients for oral bioavailability enhancement will be detailed. \r\n","button_label":"Register","image":{"id":27445,"alt":"","title":"LABO-082","caption":"","description":"","mime_type":"image/png","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1.jpg","width":2362,"height":1607,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-300x204.jpg","medium-width":300,"medium-height":204,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-768x523.jpg","medium_large-width":474,"medium_large-height":323,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-1024x697.jpg","large-width":474,"large-height":323,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/02/LABO-082-1-1038x576.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":576}},"link":"https://attendee.gotowebinar.com/register/6376360823013508108?source=WEB"},{"section":"pharmaceuticals","zone":"europe","title":"Introduction to oral BAE using lipid excipients Part I: Lipid-based formulations to address oral bioavailability issues","date":"July 5, 2022 - 8:30 am CET ","location":"Online","type":"","description":"Join us to the first part of our webinar series "Introduction to oral bioavailability enhancement using lipid excipients". 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This webinar will demonstrate the importance of formulation on skin delivery, with a strong focus on solubilizers and permeation/ penetration enhancers. 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