Names and synonyms
USP NF Name
Hard fat
EP Name
Hard fat
UNII Code (FDA)
8334LX7S21
Preferred Substance Name (FDA)
Fat, hard
Handbook of Pharmaceutical Excipients
Suppository bases, hard fat
Chemical description
Consists of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant
Key characteristics
Product form
Pellets
Melting range (°C)
33.5-35.5
Hydroxyl value (mg KOH/g)
40-50
Main functionalities
Base recrystallizes rapidly and produces harder suppository units with high mechanical resistance. Used as pessary base for numerous APIs.
Main formulation technologies
