Names and synonyms
USP NF Name
Polyglyceryl-3 diisostearate
EP Name
Triglycerol diisostearate
UNII Code (FDA)
46P231IQ
Preferred Substance Name (FDA)
POLYGLYCERYL-3 DIISOSTEARATE
Handbook of Pharmaceutical Excipients
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Chemical description
Consits of polyglyceryl-3 esters of stearic (C18) acid, the diester fraction being predominant
Key characteristics
Product form
Liquid
HLB
4.5
Main functionalities
PEG-free W/O emulsifier for topical formulations Ideal for heat-sensitive API Stabilizes and improves sensorial and texture properties Safety of use is supported by precedence of use in approved pharmaceutical products
Main formulation technologies
Topical emulsion Cold formulation process
