Names and synonyms
USP NF Name
Glyceryl monolinoleate
EP Name
Glycerol monolinoleate
UNII Code (FDA)
4763AXI84L
Preferred Substance Name (FDA)
GLYCERYL MONOLINOLEATE
Handbook of Pharmaceutical Excipients
Glyceryl monolinoleate
Chemical description
Consists of mono-, di- and triglycerides of mainly linoleic (C18:2) and oleic (C18:1) acids, the diester fraction being predominant
Key characteristics
Product form
Liquid
Viscosity (mPa.s)
120 (20°C)
HLB
1
Main functionalities
Solubilizer for lipophilic API and bioavailability enhancer. Oily vehicle for LFCS Type I (oily), Type II (SEDDS) and Type III (SMEDDS), associated with lymphatic absorption. Safety of use is inferred by GRAS status and precedence of use in approved pharmaceutical products.
Main formulation technologies
