Names and synonyms
USP NF Name
Propylene glycol dicaprolate/dicaprate
EP Name
Propylene glycol dicaprylocaprate
UNII Code (FDA)
O4446S9CRA
Preferred Substance Name (FDA)
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE
Handbook of Pharmaceutical Excipients
Pending
Chemical description
Consists of propylene glycol esters of caprylic (C8) and capric (C10) acids
Key characteristics
Product form
Liquid
Viscosity (mPa.s)
9 – 12 (20°C)
HLB
1
Main functionalities
Oily phase for topical formulations. Oily vehicle and solubilizer for solutions. Safety of use is inferred by substantial toxicological data and precedence of use in approved human and veterinary pharmaceutical products.
Main formulation technologies
Topical ointment, emulsion, microemulsion, foam.
