Names and synonyms
USP NF Name
Mixture of Lauroyl Polyoxyl-32 glycerides and PEG 6000
EP Name
Mixture of Lauroyl Macrogol-32 glycerides and PEG 6000
UNII Code (FDA)
H5ZC52369M
30IQX730WE
Preferred Substance Name (FDA)
LAUROYL PEG-32 GLYCERIDES
POLYETHYLENE GLYCOL 6000
Handbook of Pharmaceutical Excipients
Polyoxylglycerides
Polyethylene glycol
Chemical description
Consists of a small fraction of mono, di- and triglycerides and mainly PEG-32 (MW 1500) mono- and diesters of lauric acid (C12) and of PEG-150 (MW 6000)
Key characteristics
Product form
Pellets
Melting range (°C)
57-62°C
HLB
14 ± 1
CMC (mg/L, 25°C)
40
Main functionalities
Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into microemulsion—LFCS Type III (SMEDDS). Safety of use is inferred by extensive toxicological evaluations and precedence of use in approved pharmaceutical products.
Main formulation technologies
