A glyceride with an intermediate melting point containing PEG-8 esters. A powder wetting agent and lubricant for effervescent and fast-dissolving tablets.
Let’s now discover the Glittering Gummies (2745-3.04), a surprising travel-friendly format for a highlighter, made possible by Emulium® Kappa MB! Compact and easy to carry, this solid O/W emulsion is perfect for touch-ups on the go.
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It offers an ultra-bouncy effect and melting sensation thanks to Lipocire® A SG and creates a fresh and watery effect upon application. \n (97.4% natural origin)
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Craving uniqueness? The Holo Eye Liner (2758-1.11) has been designed to reveal the eccentricity living in you while reamining smudge-free and waterproof. Creamy and quick-drying, it melts seamlessly thanks to Lipocire® A SG to leave an intense purple, holographic line with long-wear properties! Emulium® Dolcea MB shows unfailing efficiency and robustness with this formula rich in pigments. \n (92% natural origin)
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Playground
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What if everyday life became a playground (again)? Gattefossé encourages more playful cosmetic application with our Cottage Cheese cream (2748-1.11) and its Squid Ink Topping (2748-2.04)! With Emulium® Dolcea MB, Acticire® MB, and EnergiNius® this creamy, yogurt-like texture delivers moisturizing and energizing benefits, perfect for daily application. Recommended once a week or once a month, mix it with 2 drops of the Squid Ink Topping, enriched with Original Extract® Ginger, to create your own detox mask! \n (99.5% natural origin)
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Experience the unexpected
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It’s time to discover new territories! Between the real and imaginary, appearances can be misleading… \n Like the Chayote-Kiwi Sorbet (2694-3.03), is it a beauty sorbet or a granita? With its light green color, you first see a food-like texture that you would love to eat. Upon initial application, you’ll feel a fresh, creamy yet powdery sensation, that leaves a dry, soft, non-tacky after-feel due to Emulium® Mellifera MB. This cushion cream brings a refreshing and intense moisturization, acts as a blur, and protects the skin from photoaging with Solastemis™. The skin appears radiant, even, and healthy. \n (99.4% natural origin)
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Alien Slime (2614-3.01) is another optical illusion! is it slime, or is it a cosmetic? Try it and you’ll be surprised by its comfortable, stringy, but non-sticky after-feel thanks to Emulium® Dolcea MB & Acticire® MB.
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Adapted for sensitive skin, it has a long playtime which is perfect for a soothing massage! It can also be used as a leave-on so that you can appreciate its nourishing properties. \n (98.2% natural origin)
\n\n","box_links":[{"title":"Inspiration 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active ingredients"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"Actifs cosmétiques | Soins du visage, soins du corps, maquillage | Gattefossé","_yoast_wpseo_metadesc":"Gattefossé propose une large gamme d'actifs et ingrédients cosmétiques pour les professionnels de l'industrie cosmétique."},"categories":[13],"tags":[],"acf":{"component":"PageProductFinderCos","type":"actives","image":{"id":13715,"alt":"","title":"actives","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives.jpg","width":1144,"height":400,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-300x105.jpg","medium-width":300,"medium-height":105,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-768x269.jpg","medium_large-width":474,"medium_large-height":166,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-1024x358.jpg","large-width":474,"large-height":166,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2017/01/actives-1038x400.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":400}},"text":"TROUVEZ L'ACTIF QU'IL VOUS FAUT","content_not_translated":false,"equivalent_fr":false,"equivalent_en":false},"_links":{"self":[{"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/pages/523"}],"collection":[{"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/pages"}],"about":[{"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/types/page"}],"author":[{"embeddable":true,"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/users/36"}],"replies":[{"embeddable":true,"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/comments?post=523"}],"version-history":[{"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/pages/523/revisions"}],"wp:attachment":[{"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/media?parent=523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/categories?post=523"},{"taxonomy":"post_tag","embeddable":true,"href":"https://www.gattefosse.com/fr/wp-json/wp/v2/tags?post=523"}],"curies":[{"name":"wp","href":"https://api.w.org/{rel}","templated":true}]}},"microemulsion":{"id":2931,"date":"2017-04-25T09:41:32","date_gmt":"2017-04-25T09:41:32","guid":{"rendered":"https://www.gattefosse.com:443/?page_id=2931"},"modified":"2021-02-05T17:12:03","modified_gmt":"2021-02-05T15:12:03","slug":"microemulsion","status":"publish","type":"page","link":"https://www.gattefosse.com/pharmaceuticals-content/microemulsion/","title":{"rendered":"Microemulsion"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"Exipients for microemulsion | Gattefossé","_yoast_wpseo_metadesc":"Understand how microemulsions are formed spontaneously by gentle mixing of oily vehicle, surfactant/cosurfactant and water."},"categories":[49],"tags":[],"acf":{"component":"PageGenericContentPharma","title":"Microemulsion","content":"
Microemulsions are thermodynamically stable systems formed spontaneously by gentle mixing of their components: oily vehicle, surfactant/cosurfactant, and water.
\n
A pseudoternary phase diagram determines the respective concentrations of the components yielding a microemulsion. Watch our video for more information on how to develop pseudoternary diagrams.
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\n
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Labrasol® is a liquid oil-in-water (O/W) surfactant (HLB=12) with excellent solubilizing capacity. It is often used in combination with a cosurfactant such as Plurol® Oleique CC 497 (HLB=3).
Our formulators have developed microemulsions for the preparation of pharmaceutical foams using propellant-free devices. Case studies with model drugs show that a foam can easily be produced with a microemulsion-based formulation.
\n","box_links":[],"useful_links":[{"text_link":"Access our video on pseudo ternary diagram","link":false,"external_link":"https://youtu.be/QWY41T3oR98"},{"text_link":"Excipients for solubilizing drugs","link":"https://www.gattefosse.com/pharmaceuticals-content/excipients-for-solubilizing-drugs/","external_link":""},{"text_link":"Excipients for topical drug delivery","link":"https://www.gattefosse.com/pharmaceuticals-range-of-products/range-of-products/","external_link":""},{"text_link":"Foams","link":"https://www.gattefosse.com/pharmaceuticals-content/pharmaceutical-foams/","external_link":""}],"":false,"content_not_translated":false,"equivalent_fr":false,"equivalent_en":false},"_links":{"self":[{"href":"https://www.gattefosse.com/wp-json/wp/v2/pages/2931"}],"collection":[{"href":"https://www.gattefosse.com/wp-json/wp/v2/pages"}],"about":[{"href":"https://www.gattefosse.com/wp-json/wp/v2/types/page"}],"author":[{"embeddable":true,"href":"https://www.gattefosse.com/wp-json/wp/v2/users/9"}],"replies":[{"embeddable":true,"href":"https://www.gattefosse.com/wp-json/wp/v2/comments?post=2931"}],"version-history":[{"href":"https://www.gattefosse.com/wp-json/wp/v2/pages/2931/revisions"}],"wp:attachment":[{"href":"https://www.gattefosse.com/wp-json/wp/v2/media?parent=2931"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https://www.gattefosse.com/wp-json/wp/v2/categories?post=2931"},{"taxonomy":"post_tag","embeddable":true,"href":"https://www.gattefosse.com/wp-json/wp/v2/tags?post=2931"}],"curies":[{"name":"wp","href":"https://api.w.org/{rel}","templated":true}]}},"applications":{"id":1340,"date":"2017-04-05T13:52:27","date_gmt":"2017-04-05T13:52:27","guid":{"rendered":"/?page_id=1340"},"modified":"2020-02-25T15:58:05","modified_gmt":"2020-02-25T13:58:05","slug":"applications","status":"publish","type":"page","link":"https://www.gattefosse.com/fr/corporate-content/applications/","title":{"rendered":"Applications"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"Support technique et formules applicatives | Gattefossé","_yoast_wpseo_metadesc":"Nos 4 laboratoires d'applications sont à votre service pour vous assister tout au long de vos projets de formulations cosmétiques et pharmaceutiques."},"categories":[48],"tags":[],"acf":{"component":"PageGenericContentCorporate","title":"Applications","content":"
\n
Les laboratoires d’applications de Gattefossé ont pour mission de démontrer les bénéfices de nos ingrédients dans des formulations prototypes et de vous apporter l’assistance technique nécessaire au développement de vos formules de soins et de médicaments. Nos experts mettent à profit leur connaissance fine de vos métiers pour reproduire vos problématiques de formulation et y répondre efficacement.
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Nos formulateurs travaillent en étroite collaboration avec notre pôle recherche et développement pour analyser le comportement de nos ingrédients cosmétiques et nos excipients pharmaceutiques et mettre en évidence leurs bénéfices en formulation. Nous sommes ainsi en mesure de proposer à nos clients des solutions innovantes et efficaces, en adéquation avec les besoins des marchés cosmétique et pharmaceutique et les réglementations en vigueur à travers le monde.
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Quatre laboratoires d’applications au service de votre capacité d’innovation
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Le groupe Gattefossé possède quatre laboratoires d’applications en France, en Chine, en Inde et aux Etats-Unis, des positions stratégiques qui nous permettent d’établir une relation étroite avec nos clients locaux.
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Ces pôles d’excellence sont chargés de vous offrir un service personnalisé et un soutien technique vous permettant d’optimiser les fonctionnalités de nos ingrédients dans vos produits cosmétiques ou pharmaceutiques. Répondant aux standards de sécurité, d’hygiène et de qualité exigés par nos domaines d’activité, nos quatre laboratoires sont équipés des mêmes technologies de pointe que celles de nos clients, garantissant ainsi la reproductibilité des procédés de fabrication.
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Nos laboratoires d’applications pharmaceutiques
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Les objectifs de nos laboratoires d’applications pharmaceutiques se déclinent en trois volets :
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Création et mise à disposition de formules d’orientation,
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Assistance-client et support en formulation,
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Formation technique à destination de notre réseau mondial et de nos clients.
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Nos formulateurs valorisent la richesse de nos excipients en développant de nombreuses formes galéniques pour différentes voies d’administration :
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Voie orale : fabrication de formes orales à libération contrôlée, amélioration de la biodisponibilité des actifs grâce à des formules lipidiques auto-émulsifiantes, développement de SELF (Self Emulsifying Lipidic Formulation) solides…
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Voie topique : formulation d’émulsions H/E et E/H, pommades, gels anhydres et caractérisation de leurs propriétés sensorielles,
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Voie rectale et vaginale : sélection des masses pour suppositoires les plus appropriées pour un actif, développement et caractérisation des suppositoires/ovules correspondants.
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Nos laboratoires d’applications cosmétiques
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Nos laboratoires d’applications cosmétiques allient savoir-faire et technicité dans le cadre d’un large éventail de missions :
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Evaluation de nos ingrédients actifs et fonctionnels en formulation,
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Qualification de nouvelles matières premières,
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Co-création de produits innovants répondant aux évolutions réglementaires et aux nouvelles tendances du marché, en collaboration avec nos équipes de R&D,
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Réalisation de formules spécifiques à la demande de nos clients,
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Développement de kits de formules autour de nos matières premières.
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Toute l’expertise galénique de Gattefossé est mise en oeuvre au quotidien pour proposer des formules originales, aux textures ancrées dans les tendances actuelles, pour tous types d’applications: soins visage, corps ou cheveux, maquillage, formules éco-responsables, produits solaires…
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L’analyse sensorielle, une expertise unique en matière de textures
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Parce que l’utilisation d’un produit de soin ou de beauté mobilise tous nos sens, Gattefossé accorde une grande importance à l’évaluation sensorielle de ses produits et formules et a développé dès 1996 son expertise en analyse sensorielle.
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Pionniers dans ce domaine, nous avons mis en place un panel d’experts spécialisés dans la caractérisation des textures ; en particulier sur les produits cosmétiques et les formulations pharmaceutiques destinées au topique. Qu’il s’agisse de nos propres formules ou de produits du marché, nos experts sont capables d’évaluer avec précision les propriétés physiques et sensorielles de n’importe quel produit et de traduire ces sensations en données objectives.
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Depuis 20 ans, nous avons ainsi créé une base de données sensorielle qui s’enrichit en permanence et nous permet de répondre aux demandes spécifiques de nos clients.
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The skin around the eyes is thinner than on any other part of our bodies, which makes it the most sensitive to change. Short nights, stress, and fatigue all contribute to puffiness and dark circles, affecting 80% of all women and as much as 50% of all men. Undereye bags and dark circles are the result of several disorders, including weak blood and lymphatic capillaries, poor drainage of interstitial fluids, skin sagging, and a reduction in microcirculation.
Cytobiol™ Lumin-Eye is an active blend based on the complementary benefits of three components: ash tree bark extract, vitamin B3 and organic silicon.
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Preservative free.
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The high ash (Fraxinus excelsior) is a large tree commonly found in European forests. It draws its name from Latin fraxinus (“lightning”) because its height of up to 40 m attracts lightning.
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Its bark contains esculin and fraxin, two heterosides known to actively decrease the permeability of blood capillaries. These compounds give Cytobiol™ Lumin-Eye veinotonic and vasculoprotective properties. Moreover, fraxin and esculin have antioxidant activity that helps protect the blood capillaries while simultaneously resisting the breakdown of hemoglobin to reduce coloration under the eyes.
In vivo tests prove Cytobiol™ Lumin-Eye effectively reduces:
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volume of undereye bags by up to 30%,
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color intensity of dark circles by 18%,
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area of dark circles by 15%.
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Gatuline® Link n Lift redonne au regard l’expression d’une jeunesse envolée.
Premier actif anti-âge cosmétique obtenu par la technologie NaDES (Natural Deep Eutectic Solvents) et issu de la fleur de marronnier d’Inde, Gatuline® Link n Lift est riche en molécules actives présentes uniquement dans cette fleur.
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action en profondeur, dans le derme, au niveau des fibroblastes pour aider la peau à lutter contre la dégradation de sa matrice;
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renforcement de l’intégrité et de l’activité de la jonction dermo-épidermique par une stimulation de la synthèse de l’ensemble des composants impliqués dans la cohésion derme-épiderme et dans les voies de communication.
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Raffermit le contour de l’oeil
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Restructure et lisse la peau
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Améliore la qualité globale de la peau et le confort
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Action rapide
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Exposée au stress environnemental, la fonction barrière de la peau est altérée, facilitant la pénétration d’irritants, et augmentant la Perte Insensible en Eau (PIE). Par conséquent, la peau devient sèche et sensible, avec l’apparition de rougeurs et de sensations de tiraillement. Il y a un besoin croissant d’ingrédients de texture apaisants qui réduisent la sensibilité de la peau face aux agressions et permettant l’utilisation de produits de soin et de maquillage sans réaction, ni inconfort.
\n
Emulium® Dermolea MB, émulsionnant H/E, réduit le stress cutané et apaise durablement grâce à sa composition lipidique unique riche en stérols et triterpènes. Hautement hydratant et protecteur, cet ingrédient est préconisé pour renforcer la fonction barrière de la peau. Utilisé jusqu’à 4%, il convient à tous les types de peaux, dans les climats humides comme secs.
\n
Emulium® Dermolea MB a été créé grâce aux connaissances exclusives de Gattefossé sur la technologie du beurre de cire. La cire de candelilla, la cire de son de riz et la cire de jojoba ont été sélectionnées pour leurs propriétés complémentaires et elles ont été fonctionnalisées avec du polyglycerol-3.
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Composé de lipides végétaux proches de ceux de la surface de la peau, riches en triterpènes et stérols pentacycliques anti-inflammatoires, Emulium® Dermolea MB forme un film fin et compatible avec la peau, prouvé pour réduire le stress environnemental cutané. Hautement hydratant et protecteur, cet émulsionnant renforce la fonction barrière cutanée et apporte une sensation d’apaisement de longue durée
Capable d’émulsionner jusqu’à 40% de phase grasse, Emulium® Dermolea MB permet de créer une large gamme de textures allant du spray au beurre épais. Il est adapté aux formules de soins, de maquillage, aux formules solaires, capillaires, et au soin du cuir chevelu. Sous forme de granulés, il est très facile à mettre en œuvre et forme des émulsions stables. L’utilisation d’un gélifiant est recommandée pour une meilleure stabilité, notamment à haute température.
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Adapté à tous types de climats
\n
Profil sensoriel similaire en milieu tempéré et en climat tropical humide
Crée un film hydratant fin et compatible avec la peau
\n
Renforce la fonction barrière cutanée
\n
Facile à mettre en œuvre en laboratoire et en production
\n
Protège contre le stress inflammatoire induit par la pollution
\n
Hydratation longue durée
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Effet apaisant à long terme
\n
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Large gamme de textures de la formule sprayable aux baumes épais
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Marques dermatologiques, produits pour peaux sensibles et pour peaux matures
\n
Soins de la peau, maquillage, soins solaires, soins capillaires et soins du cuir chevelu
\n
Formules végan, certifiées biologiques et facilement biodégradables
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A nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.
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Propylene Glycol Mono and Dicaprylate NF \n[May also be labeled as Propylene Glycol Monocaprylate (type I) NF until December 1, 2026]
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PROPYLENE GLYCOL CAPRYLATE
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Propylene glycol monocaprylate
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Consists of propylene glycol esters of caprylic acid (C8), composed of mono- and diesters.
Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulation. Safety of use is inferred by precedence of use in approved pharmaceutical products.
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Les lois de la gravité sont inévitables mais leurs effets secondaires sur notre peau n’ont pas à l’être. EleVastinTM est la solution à l’affaissement du visage induit par la gravité. L’ingrédient cible des protéines essentielles pour la synthèse et le maintien d’un réseau de fibres élastiques fonctionnelles. Par ce biais, il renforce l’élasticité de la peau et lui apporte le soutien nécessaire pour lutter contre cette pression vers le bas.
\n
Les contours du visage sont ainsi mieux dessinés, les rides verticales et profondes sont réduites et un visage d’apparence plus jeune est restauré.
EleVastinTM est issu des tiges feuillues de Murraya koenigii, une plante utilisée en médecine ayurvédique et en cuisine. La plante est récoltée sur l’île de la Réunion, sur des parcelles préservée de tout intrant (sans traitement ni pesticide).
\n
Grâce à l’utilisation d’un mélange de solvants d’origine végétale de type LTTM (Low Transition Temperature Mixture) et à un procédé d’extraction raisonné, un riche complexe de phyto-molécules est obtenu.
\n
L’ingrédient est approuvé COSMOS et affiche un contenu d’origine naturelle de 100% selon la norme ISO 16128.
Evalué sur un panel de 37 femmes présentant une peau mature, EleVastinTM limite efficacement l’impact de la gravité sur la partie basse du visage et réduit le relâchement et les rides verticales profondes.
\n
Dans 75% des cas, les volontaires paraissent plus jeunes à la fin de l’étude.
Hard fat suppository base that provides excellent chemical stability with acidic APIs and high crystallization rate. A versatile base with precedence of use with a wide range of APIs.
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Nippon story: what does “J-Beauty” mean?"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"The expertise and quality of Japanese cosmetics gives an answer to a rising demand for natural, healthy products."},"categories":[56],"tags":[],"acf":{"content_not_translated":false,"equivalent_fr":false,"equivalent_en":false,"component":"PageGenericContentCos","title":"A nippon story: What does “J-Beauty” mean?","content":"
After the success of playful, off-beat and colorful products from the K-Beauty wave, Japanese rituals and products are now entering the Western market(1). The expertise and quality of Japanese cosmetics – well known and famous in Asia for decades – gives an answer to a rising demand for natural, healthy products as well as integrity and simplicity in Western countries.
\n
When tradition meets innovation
\n
Well known for its ancient traditional rituals, especially from Geishas and Kabuki theatre, the country of the rising sun allies the old with the new.
\n
\n
Technology-driven, Japanese brands use key natural ingredients such as green tea, camellia oil or rice, and enhance their potential using science. Their guidelines rely on few ingredients and R&D capacities to optimize cosmetic results.
\n
Moreover, highly concerned by product composition, and aware of how their body and skin work, Japanese people look for high-quality and reliable offers rather than trends. To meet this level of requirement, the focus is set on science and a strict rule: “one claim, one research”, thus providing honesty and integrity to consumers.
\n
A matter of patience
\n
\n
At a time where we constantly run and urge ourselves, there is a huge need for relaxation, and slowing down a little. \n Inspired by three principles: Simplicity (Kanso), Elegance (Shibui), and Tranquility (Seijaku), J-Beauty is all about minimalist formulas, and light textures. \n No more profusion: moderation and fewer products are at the chore of this new wave. The Japanese promote quality rather than quantity, by applying less products and executing methodic application techniques such as massages.
\n
Japanese rituals
\n
Focused on healthcare and prevention – unlike the Western correcting approach- J-Beauty is based on in depth results, patience and simplicity. \n Skincare is at the heart of the Japanese routine, as beauty relies on a healthy complexion which means a clean, moisturized and protected skin. Japanese women especially preserve and take care of their skin by avoiding sun exposure, and using face masks or lotions for in depth hydration(2). \n Cleansing is also a major concern for Japanese beauty consumers. At the center of the beauty ritual as it brings peacefulness, humility and self-awareness, bathing is a very important step in the Japanese culture, and can easily take hours. It is considered as a privileged moment, where people can focus on themselves, stimulate their senses (smell especially) and take care of their skin too. This bathing ritual is then followed by a cold shower to close the pores.
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Read through our articles by selecting one or several topics below.
A glyceride with an intermediate melting point used as a matrix agent for sensitive APIs and a viscosity-increasing agent in oral and topical formulations.
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Hard fat
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Hard fat
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FAT, HARD
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/
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Consists of mono-, di- and triglyceride esters of fatty acids (C8 to C18), the triester fraction being predominant
Matrix-forming agent for protection of APIs sensitive to oxidation, humidity, or light. Consistency agent in oral and topical formulations. Safety of use is inferred by precedence of use in approved pharmaceutical products.
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Nature is a constant inspiration for cosmetics ingredients, but plants are not the only sources of natural actives. Mineral Matters™ liquid stone extracts apply special technology to extract important minerals from precious stones and make them bioavailable to the skin. The result is a unique line of substantiated stone actives that enhance and protect. Zin’Cîte™ is a zinc complex extracted from smithsonite that offers long-term protection by shielding DNA and preventing glycation. See the other actives in this Mineral Matters™ line:
Smithsonite is a 100% natural zinc carbonate (ZnCO3) stone sourced in Mexico. Characterized by a silky or pearly luster, this stone can reflect light or appear transparent, depending on the specimen. Smithsonite can be found in different colors, from turquoise to pink.
\n
\n
A unique process allows us to obtain a stable, bioavailable zinc-rich liquid active from smithsonite. Preservative free.
Solubilizer and O/W surfactant for microemulsion. Able to form light foams with pump device (no gas required). Safety of use is inferred by extensive toxicological evaluations and precedence of use.
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Les peaux mixtes à grasses et à tendance acnéique ont aussi droit à une « peau parfaite » ! Adolescents, jeunes adultes, variations hormonales ou climat chaud qui accentuent cette nature… tous militent pour une peau zéro défaut! Grâce à la synergie de ses 3 composants actifs, Cytobiol™ Iris A² est la solution idéale pour une peau parfaite.
La gamme des Cytobiol™ repose sur l’association synergique de 3 composants complémentaires : un extrait végétal + une vitamine + un oligoélément. Ciblant les peaux mixtes à grasses à tendance acnéique, Cytobiol™ Iris A² associe:
Ce complexe purifie la peau, réduit les imperfections et resserre les pores. Le grain de peau est affiné, la brillance est réduite, l’apparence globale de la peau est améliorée.
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\n
Cible les imperfections
\n
Effet blur
\n
Minimise les pores
\n
Purifie
\n
Réduit l’aspect brillant de la peau
\n
Lutte contre les imperfections
\n
Améliore la texture de la peau
\n
Crée un fini mat
\n
\n","applications":"
\n
Traitements des peaux à tendances acnéiques
\n
Peaux mixtes à grasses
\n
Soins matifiants
\n
Crèmes alphabets : BB, CC crèmes
\n
Perfecteurs de peaux
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Hard fat suppository base with high melting point, optimized for APIs that decrease the mass melting point, such as liquid lipophilic APIs.s.
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Revendication n°1 en Asie, la lutte contre les tâches pigmentaires devient également prédominante en Europe, à un moment où les abus de soleil et les excès passés des années 60, 70 et 80 laissent leurs marques indélébiles sur des consommatrices en quête de teint frais et homogène.
\n
Pour répondre à cette attente globale du marché, Gattefossé a créé Gatuline® Spot-Light, un actif végétal innovant agissant à la fois sur les causes épidermiques et dermiques de l’hyperpigmentation photo-induite.
Gatuline® Spot-Light est un extrait végétal issu de deux plantes :
\n
\n
\n
Sophora flavescens, une plante d’origine asiatique largement utilisée en médecine traditionnelle chinoise.
\n
\n
\n
Actinidia chinensis : le kiwi, dont l’eau de constitution possède des vertus pro-éclaircissante et pro-hydratante (réduit les activités de la tyrosinase et de la hyaluronidase).
\n
\n
\n
\n
Gatuline® Spot-Light bénéficie d’une teneur garantie en deux molécules à l’efficacité reconnue : les flavanones (exprimées en sophoraflavanone G) et la matrine. La méthode d’extraction utilisée permet de tirer le meilleur de ces plantes, sur des solvants d’origine végétale et dans le respect de l’environnement. Sans conservateur.
Réduit la visibilité et le nombre de taches de vieillesse
\n
Diminue l’apparence des taches sombres
\n
Agit sur les causes épidermiques et cutanées des taches de vieillesse
\n
Éclaircit le teint
\n
\n","applications":"
\n
Traitements ciblés par âge et place
\n
Perfecteurs de peau, fondations et correcteurs
\n
Produits éclaircissants
\n
Crèmes alphabétiques
\n
Lignes anti-âge globales
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Agent de texture naturel et durable, Lipocire™ A SG donne du corps aux formules cosmétiques et leur confère un toucher plus onctueux, ultra fondant.
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Une expérience sensorielle unique dans de nombreuses applications soin et maquillage.
Beurre végétal texturant, Lipocire™ A SG est issu de l’hydrogénation et de l’inter-estérification d’huiles de palme et de palmiste, extraites des fruits et des graines du palmier à huile. Relipidants et nourrissants, ces lipides filmogènes présentent une excellente affinité avec la peau et permettent de reconstituer le film protecteur hydrolipidique. Ils apportent douceur et confort à la peau et aux formulations.
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Gattefossé n’utilise que des huiles de palme et de palmiste certifiées RSPO Segregated (SG) (Roundtable on Sustainable Palm Oil). Cette certification garantit que les huiles proviennent exclusivement de plantations gérées durablement.
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\n
Le fruit du palmier a la peau rouge foncé et la chair jaune-orange, il est particulièrement riche en éléments nutritifs. La pulpe du fruit et l’amande dans son noyau ont tous deux une teneur élevée en triglycérides (> 50%).
\n
Autres grades disponibles :
\n
\n
Lipocire ™ CM SG a un point de fusion légèrement supérieur et est préconisé pour les formulations de plus grande rigidité : par exemple, sticks ou poudres pressées.
\n
Lipocire ™ DM SG a un point de fusion supérieur aux deux autres grades. Il est conseillé de l’utiliser pour les formulations avec une solidité encore plus grande, comme les crayons de maquillage.
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Original Extracts™ are living waters designed especially for cosmetic formulations. Directly obtained from fruits or plants, they contain well-balanced amounts of trace elements, mineral salts, and essential oils. Extracted using targeted technologies, without solvents or contact with external water, they are pure and all-natural. They can partially or completely substitute the water of cosmetic formulations.
Obtained without maceration or addition of external water, these plant and fruit waters can partially or completely substitute the water of cosmetic formulations. Produced from 100% organic fruit, organic Original Extracts™ are the ideal ingredients for the development of certified organic cosmetics.
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Modified- or sustained-release matrices are designed to release a drug slowly over an extended period of time. Formulations must be robust to ensure drug release over time and avoid dose-dumping. Lipid-based matrices are water-insoluble and do not swell or erode when in contact with aqueous media. When used as sustained-release agents, they form an inert matrix from which the drug diffuses slowly.
\n
Advantages of Gattefossé’s modified-release agents:
\n
• Drug release is a function of diffusion, which enables simple product design and offers both straightforward modulation of drug release and high reproducibility. • Tablets are biopharmaceutically robust as the lipid matrix is not sensitive to physiological variations (e.g., pH, digestive processes, alcohol level). • Agents are suitable for a wide range of processing techniques, including direct compression, granulation, melt coating, hot melt extrusion, and capsule molding.
finely atomized lipid excipient powder of well-defined, reproducible composition and particle size
\n
used at proportion of 10%–40%, depending on drug solubility and diluent properties
\n
suitable for direct compression, granulation, and hot processes (i.e., hot melt coating, granulation, and extrusion)
\n
crystalline material with narrow melting range (∼70 °C) and rapid recrystallization, ideal for hot melt processes
\n
GRAS status and precedence of use with many APIs (FDA IID)
\n
\n
We can provide technical guidelines that offer useful tips on SR formulation development and numerous case studies with model drug molecules, e.g., bupropion HCl, levodopa, metformin HCl, metoprolol succinate, niacin, and theophylline.
finely atomized lipid excipient powder of well-defined, reproducible composition and particle size
\n
crystalline material with narrow melting range (∼55 °C) and rapid recrystallization, suitable for use in hot processes (i.e., hot melt coating, extrusion, and capsule molding)
\n
GRAS status and precedence of use with many APIs (FDA IID)
crystalline material with narrow melting range (∼60 °C) and rapid recrystallization, suitable for use in hot processes (i.e., hot melt coating, extrusion, and capsule molding)
\n
GRAS status and precedence of use with many APIs (FDA IID)
\n
\n
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A trained panel and validated methods for reliable results
\n
\n
Our sensory panel brings together over a dozen trained staff members, both men and women. They test new formulations approximately twice a week. The assessments are carried out using specific protocols and standardized procedures, and the results are statistically analyzed.
\n
Tests cover vision and touch, and they evaluate the following criteria:
\n
\n\n
\n
Initial touch \n
\n
pick-up
\n
texture
\n
creaminess
\n
\n
\n
\n
\n
During application\n
\n
spreadability
\n
tackiness
\n
play time
\n
greasiness
\n
softness
\n
absorption
\n
\n
\n
After absorption\n
\n
residual film
\n
tackiness
\n
greasy after-feel
\n
soft after-feel
\n
shine
\n
\n
\n
\n\n
\n"},{"wysiwyg":"
The power of sensorial mapping
\n
\n
\n
\n
This sensorial map shows the results with cream formulations formulated with different Gattefossé pharmaceutical-grade emulsifiers. It enables direct and visual comparison and can help to select the emulsifier or appropriate prototype formulation.
\n
Click on the image to enlarge.
\n
\n
For more information on how to develop formulas for optimized texture and sensory properties, please see our topical formulation section.
\n
\n
\n
\n
\n"}]},"_links":{"self":[{"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/pages/3654"}],"collection":[{"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/pages"}],"about":[{"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/types/page"}],"author":[{"embeddable":true,"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/users/9"}],"replies":[{"embeddable":true,"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/comments?post=3654"}],"version-history":[{"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/pages/3654/revisions"}],"wp:attachment":[{"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/media?parent=3654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/categories?post=3654"},{"taxonomy":"post_tag","embeddable":true,"href":"https://www.gattefosse.com/procedes-par-fusion/wp-json/wp/v2/tags?post=3654"}],"curies":[{"name":"wp","href":"https://api.w.org/{rel}","templated":true}]}},"excipients-for-optimizing-texture-and-sensorial-experience":{"id":3897,"date":"2017-05-04T07:32:31","date_gmt":"2017-05-04T07:32:31","guid":{"rendered":"https://www.gattefosse.com:443/?page_id=3897"},"modified":"2021-04-07T10:09:29","modified_gmt":"2021-04-07T08:09:29","slug":"excipients-for-optimizing-texture-and-sensorial-experience","status":"publish","type":"page","link":"https://www.gattefosse.com/pharmaceuticals-content/excipients-for-optimizing-texture-and-sensorial-experience/","title":{"rendered":"Excipients for Optimizing Texture and Sensorial Experience"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"Excipients for optimizing texture of topical dosage forms | Gattefossé","_yoast_wpseo_metadesc":"Discover our range of excipients to improve texture and sensorial properties of topical dosage forms and positively impact patient experience."},"categories":[49],"tags":[],"acf":{"component":"PageGenericContentPharma","title":"Excipients for Optimizing Texture and Sensorial Experience","content":"
Improvement of topical dosage form texture and sensorial properties is an increasingly common formulation objective:
\n
\n
Improved texture and sensorial properties positively impact patient experience and adherence to treatment.
\n
A growing number of topical medicines switch over to OTC, where brand differentiation and patient choice comes into play.
\n
Innovation can be achieved by reformulating the dosage form with optimized texture and sensorial features.
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Sensorial mapping evaluates product’ aspects during application and absorption. We have developed a database of prototype formulations with different textures and sensorial profiles. This helps our customers select formulations with excellent texture and sensorial properties. Dermacare is a collection of simple and effective prototypes of creams, emulgels, and lotions with optimized texture and sensorial properties. Our database also includes formulations for foams, sprays, microemulsions, and gels. Contact Gattefossé for our Dermacare guidelines.
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We know that ingredients or even formulation type—for example, cream versus emulgel—can directly affect sensorial properties. Sensorial panel experts at Gattefossé Application Laboratories can study these factors.
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Impact of Granulation Solvent on Release Performance of Dual Matrix Extended Release Tablets of Highly Water Soluble Drugs Formulated using Compritol® 888 ATO and Methocel® as Release Retarding Agents
The purpose of this study is to evaluate the impact of different granulation solvents on the performance of dual extended- release matrix tablets, formulated using a combination of Compritol® 888 ATO and Methocel® K100M, with two model APIs:
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highly water-soluble high dose (1000 mg) Metformin Hydrochloride
Selecting efficient pharmaceutical binder for developing robust extended-release matrices of Compritol® 888 ATO prepared using wet granulation technique : Part 1 Studying impact on granule & tablet properties
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K. Deshmukh, A. Shrivastava, S. Banerjee, R. Tiwari, S. Bambarkar, N. Farah Gattefosse India Pvt. Ltd., Mumbai, INDIA, Gattefosse SAS, Lyon, FRANCE
Selecting efficient pharmaceutical binder for developing robust extended-release matrices of Compritol® 888 ATO prepared using wet granulation technique: Part 2 Studying impact on dissolution profiles of ER tablets of different API’s
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K. Deshmukh1, A. Shrivastava1, S. Banerjee1, R. Tiwari1, S. Bambarkar1, N. Farah2 1Gattefosse India Pvt. Ltd., Mumbai, INDIA, 2Gattefosse SAS, Lyon, FRANCE
Influence of Formulation Factors and Compression Force on Release Profile of Sustained Release Metoprolol Tablets using Compritol® 888 ATO as Lipid Excipient
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Shilpa N. PATERE, Chhanda J. KAPADIA and Mangal S. NAGARSENKER Indian J Pharm Sci 2015;77(5): 620-625 Release profile of metoprolol from sustained release tablets using Compritol 888 ATO as SR lipid matrix agent showed high reliability. Different sources of active ingredient and batches of Compritol were evaluated at different compression forces and in dissolution media containing or not ethanol. The formulation appeared to be very robust and is not affected by these variables. Therefore Compritol offers great potential in the formulation of reliable SR tablets.
Smart strategies for sustained release tablets: Compritol® 888 ATO
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White paper – May 2014 This white paper gives an overview of how Compritol® 888 ATO provides clinically relevant sustained drug release profiles along with biopharmaceutical, formulation and manufacturing advantages.
Solid lipid excipients – matrix agents for sustained drug delivery.
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Yvonne Rosiaux, Vincent Jannin, Sophie Hughes, Delphine Marchaud Journal of Controlled Release Volume 188, 28 August 2014, Pages 18–30
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This review article focuses on the utility of lipid excipients in solid sustained drug delivery systems with emphasis on the efficiency and robustness of these systems with respect to: (i) the choice of the manufacturing process and impact on drug release, (ii) the fundamental drug release mechanisms, (iii) resistance of the drug formulation under physiological conditions and (iv) long-term stability. Understanding the functionality of these versatile excipients in formulation is elementary for the development of highly robust lipid-based sustained release medicines
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Founded in Lyon, France, in 1880, Gattefossé is a leading provider of specialty ingredients and formulation solutions for the beauty and health care industries worldwide. Our history is built on our founders’ deep commitment to sustainability, innovation, and service. Specialists in lipid chemistry and plant extraction, we create effective natural actives and functional lipid excipients. We work diligently to guarantee the quality and reliability of our ingredients while providing our customers with all the support and resources they need to make successful products that address global consumers’ demands.
For nearly 140 years, our strategy of continuous investment in research, development, and applications has driven our capacity to innovate. Gattefossé customers benefit from the company’s unique know-how and ability to stay one step ahead of market trends in the personal care and pharmaceutical sectors.
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You can meet Gattefosse India team at booth SA3, Block A.
\n
The team shall be represented by: \n – Anurag Tyagi – Regional Business Manager – North India & Nepal \n – Ketkee Deshmukh, Ph. D. (Tech) – Technical Manager – Pharmaceuticals \n – Agnivesh Shrivastava, Ph. D. (Tech) – Technical Manager – Pharmaceuticals.
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Also, APPON-Quality Circle has given an opportunity to Gattefosse India Pvt. Ltd to conduct Technical Seminar, as per the below schedule:
\n
1. Enhancement of Bioavailability and dissolution by using lipid excipients to be presented by Ketkee DESHMUKH, Ph. D. (Tech), Technical Manager – Pharmaceuticals on 1st March 2019 between 1:00 PM and 1:45 PM
\n
2. Innovative solutions for Challenging Topical Formulations to be presented by Agnivesh Shrivastava Ph. D. (Tech), Technical Manager – Pharmaceuticals on 1st March 2019 between 1:45 PM and 2:30 PM
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Texture is key.
\n
Responsible for triggering different sensations and reactions, texture is truly the charm card, the major contributor to consumer seduction. The initial impression of the texture is what influences consumers’ choice of personal care products. The long-term appreciation upon use is what makes the consumer faithful to a cosmetic product.
\n
The texture also plays a significant role in the perception of efficacy. Finally, it can also actively contribute to increase skin benefit, with so-called smart textures that possess inner biological activity, for example moisturizing properties.
\n
\n
The role of sensory analysis in cosmetics
\n
\n
As sensory impression plays an important role in the consumer’s purchase behavior, it is essential to be able to identify and describe the sensory properties of a cosmetic product.
\n
Sensory analysis is a scientific discipline used to measure, analyze and interpret the characteristics of a product as they are perceived by the five senses. It allows to obtain a full sensory profile of a cosmetic product.
\n
\n
Sensory analysis at Gattefossé \n
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Gattefossé attaches great importance to the sensorial evaluation of its products and formulas and has been developing its expertise in sensory analysis since 1996. Gattefossé created its own group of trained panelists, composed of a dozen experts, using analytical methods to sensorially characterize the products with precision and reproducibility. They can accurately assess the physical and sensorial properties of any product and translate these impressions into objective data, regardless of whether they are evaluating our own formulas or other products on the market.
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The products are evaluated following specific steps and criteria. It starts with a visual evaluation, before measuring the behavior of the product at first touch, then during application and finally, after absorption. Here is how these criteria are evaluated by our trained panelists:
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First touch:
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During application:
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After absorption:
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Our sensory database has been constantly enriched over the course of twenty years and spans over 400 formulations to help us best respond to all customer requests.
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