Linoleoyl Polyoxyl-6 glycerides
Linoleoyl Macrogol-6 glycerides
CORN OIL PEG-6 ESTERS
Consists of mono-, di- and triglycerides and PEG-6 (MW 300) mono- and diesters of linoleic (C18:2) acid
70 – 90 (20°C)
Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion—LFCS Type II (SEDDS). Combine with Labrasol® ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS). Safety of use is inferred by substantial toxicological data and precedence of use in approved pharmaceutical products.