SEDDS for oral peptide delivery

The challenges of oral peptide delivery

For oral peptide therapeutics to be effective, formulations must:

  • prevent peptide degradation in the gastro-intestinal tract
  • promote peptide permeability

SEDDS: a simple and efficient solution

Self emulsifying drug delivery system (SEDDS):

  • consists of a mixture of oils, surfactants and solvents designed to solubilize the drug throughout the digestion process
  • effective protection from enzyme degradation and glutathione reduction
  • permeate through the intestinal mucus
  • enable high drug payload