Discover Dermasol and learn how to formulate topical dosage forms for efficient skin penetration.
Three main steps govern drug diffusion from the formulation to the skin:
- Solubility: the formulation must solubilize a sufficient amount of drug to reach the effective concentration at the target site
- Partition: the drug must partition out of the delivery vehicle into the upper layers of the SC
- Diffusion: the drug molecule diffuses through the SC mainly via the intercellular path
Discover Gattefossé range of excipients for skin penetration