Bi-gel

Bi-gels consist of an intimate mixture of an aqueous gel and an oily gel.

Due to their dual nature, bi-gels are associated with the following advantages: 

• Suitable for lipophilic and hydrophilic drugs 
• Better drug absorption through the skin  
• Cooling and moisturizing effect 
• Improved spreadability

Key ingredients

Emulfree® duo  

• A stablizing agent for the oily phase of bi-gel 
• PEG-free excipient 
• Processable at room temperature 

• Use at 1 – 8% of the formulation 

Compritol® 888 pellets 

• Consistency agent for oily phase in topical formulations 
• High melting point 65-77°C 

Geleol™ Mono and diglyceride NF 

• Consistency agent 
• Intermediate melting point 54-64°C 

Transcutol® P  

• Solubilizer and penetration enhancer for a wide range of molecules 

Lauroglycol™ FCC 

• Solubilizer and penetration enhancer 

Labrafac™ Lipophile WL 1349 

• Oily vehicle in topical formulations 
• Solubilizer 
• Improves skin feel and enhances spreadability while providing  a melting sensation.

Suppocire® A 

• Hard fat  
• Improves the texture and enables a smooth and easy application on the body