Publications on taste-masking

List of Gattefossé publications on taste-masking

High shear blending with glyceryl distearate provides individually coated drug particles for effective taste masking

Yvonne Rosiaux, Amandine Forest, Jean-Michel Girard, Carole Deleglise, Liz Sheehan and Delphine Marchaud
Journal of Drug Delivery Science and Technology 48 (2018) 437–449

In this study the authors used:
– A design of experiment, to evaluate the effect of process parameters (blending speed, chopper speed and coating time) on drug particle size.
– Potassium chloride as model drug.

The study showed:
– Individual particle coating was achieved at 450 rpm with 20% glyceryl distearate (Precirol® ATO 5) at 48°C
– High shear coating is as efficient as fluid bed coating for taste masking
– A trained sensory panel confirmed the effectiveness of the process on taste masking

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HIGH SHEAR COATING:
A VERSATILE TASTE-MASKING PROCESS

C Morin and Y Rosiaux

www.ondrugdelivery.com,  N°88 July 2018
Copyright © 2018 Frederick Furness Publishing Ltd
 

Taste-masked drugs for pediatric medicines through lipid  coating

Rosiaux Y., Forest A., Girard J.M., Deleglise C., Marchaud D.

AAPS 2017

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Efficient taste masking through high shear coating

Rosiaux Y., Forest A., Girard J.M., Deleglise C., Marchaud D.

EuPFI 2017

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