American DDF Summit
Visit Gattefossé at the 16th American Drug Delivery and Formulation Summit and discover new ways to expand your formulation toolbox.
Learn how our solutions enable both small and large molecule delivery through improved solubility, permeation enhancement, lymphatic uptake, and food effect mitigation.
Interested in a Free Ticket?
Attend Our Featured Presentation
Overcoming Oral Bioavailability Barriers with Lipid-Polymer Formulations
Nick DiFranco, MEM
Senior Marketing Manager
Masumi Dave, PhD
Senior Lab Manager
As pharmaceutical pipelines shift toward increasingly complex APIs, including poorly permeable small molecules and emerging peptide therapies, new formulation tools are needed. Poor in vivo translation, limited permeability, and food effect variability are significant roadblocks to clinical viability and patient adherence.
To overcome these barriers, formulators are expanding the role of lipid excipients to oral solid dosage forms. By marrying the structural benefits of polymers with the biological advantages of lipids, developers can achieve superior performance using proven chemistries and processing techniques.
This presentation provides a practical roadmap for utilizing lipid-polymer systems in next-generation oral solid dosage forms. Attendees will learn:
- How to harness lipid-polymer synergies to rescue challenging APIs
- Practical techniques for introducing lipids into ASDs
- The role of new solid surfactant chemistries in driving permeation and absorption
- Real-world HME case studies demonstrating how lipid excipients increase drug loading and improve release alongside polymers
Discover how integrating lipid functionality with polymeric systems can help you bypass traditional bioavailability bottlenecks and deliver highly effective, patient-centric oral therapeutics.