Labrafac™ lipophile WL 1349

An oily vehicle and solubilizer of lipophilic APIs for oral, topical, and parenteral lipid-based formulations (LBFs).

Names and synonyms

USP NF Name

Medium chain triglycerides

EP Name

Triglycerides medium chain

UNII Code (FDA)

C9H2L21V7U

Preferred Substance Name (FDA)

MEDIUM-CHAIN TRIGLYCERIDES

Handbook of Pharmaceutical Excipients

MEDIUM-CHAIN TRIGLYCERIDES

Chemical description

Consists of medium-chain triglycerides of caprylic (C8) and capric (C10) acids

Key characteristics

Product form

Liquid

Viscosity (mPa.s)

25 – 33 (20°C)

HLB

1

Main functionalities

Oily vehicle in LFCS Type I, Type II (SEDDS), and Type III formulations (SMEDDS).
Oil phase for topical formulations.
Oily vehicle and solubilizer for solutions (parenteral, auricular).
Safety of use is inferred by food additive status and precedence of use in approved pharmaceutical products.